INT194779

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.14
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.62
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (VAV1) plasma membrane (VAV1)
Anatomy Link Frequency
T-cells 2
VAV1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 2 97.00 Very High Very High Very High
COX2 6 94.20 High High
cytokine 34 49.16 Quite Low
Inflammation 30 5.00 Very Low Very Low Very Low
chemokine 8 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 89 98.56 Very High Very High Very High
Breast Cancer 8 80.56 Quite High
Metastasis 16 76.32 Quite High
Colon Cancer 124 50.00 Quite Low
Recurrence 20 17.60 Low Low
Apoptosis 9 6.76 Low Low
INFLAMMATION 33 5.00 Very Low Very Low Very Low
Autoimmune Disease 14 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Stress 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ARHGDIB, working with vav 1 guanine nucleotide exchange factor (VAV1), activates the nuclear factor of activated T-cells 1 (NFAT1) and results in transcription regulation of the tumor-related gene cyclooxygenase (COX2).
VAV1 Binding (working) of in T-cells associated with cancer and cox2
1) Confidence 0.14 Published 2010 Journal Cancer Informatics Section Body Doc Link PMC2918356 Disease Relevance 0.81 Pain Relevance 0.18
ARHGDIB, working with vav 1 guanine nucleotide exchange factor (VAV1), activates the nuclear factor of activated T-cells 1 (NFAT1) and results in transcription regulation of the tumor-related gene cyclooxygenase (COX2).
1 guanine nucleotide exchange factor Binding (working) of in T-cells associated with cancer and cox2
2) Confidence 0.12 Published 2010 Journal Cancer Informatics Section Body Doc Link PMC2918356 Disease Relevance 0.81 Pain Relevance 0.18
CD28 co-stimulation augments the recruitment of Vav to LAT and Zap-70 and increases Zap-70 mediated Vav phosphorylation [23].
Vav Binding (recruitment) of
3) Confidence 0.08 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526596 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox