INT194806

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAPK1, CD28) nucleoplasm (MAPK1) mitochondrion (MAPK1)
DNA binding (MAPK1) microtubule organizing center (MAPK1) extracellular space (Il4)
Anatomy Link Frequency
T cells 2
MAPK1 (Homo sapiens)
CD28 (Homo sapiens)
Il4 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 34 95.60 Very High Very High Very High
Inflammation 30 80.88 Quite High
Arthritis 3 6.88 Low Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity Pneumonitis 1 95.08 Very High Very High Very High
Sprains And Strains 1 91.68 High High
INFLAMMATION 31 80.88 Quite High
Disease 10 79.84 Quite High
Autoimmune Disease 14 68.96 Quite High
Arthritis 3 6.88 Low Low
Hypersensitivity 7 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have recently shown that in human memory CD4 T cells, stabilization of IL-4 and IL-13 mRNA by CD28 stimulation is mediated by p38 MAPK [60].
p38 MAPK Positive_regulation (mediated) of CD28 Positive_regulation (stabilization) of IL-4 in T cells
1) Confidence 0.08 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526596 Disease Relevance 0.42 Pain Relevance 0.13

General Comments

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