INT194827

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.12
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL13, Gata3) anatomical structure formation involved in morphogenesis (Gata3) cell morphogenesis (Gata3)
DNA binding (Gata3) cell-cell signaling (IL13) cytoplasm (IL13)
IL13 (Homo sapiens)
Gata3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 34 71.64 Quite High
Inflammation 30 55.00 Quite High
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thymoma 1 65.52 Quite High
INFLAMMATION 31 55.00 Quite High
Asthma 3 24.88 Low Low
Autoimmune Disease 14 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Hypersensitivity 7 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intensive investigations have demonstrated the fundamental function of GATA-3 in Th2 immune regulation and have shown that GATA-3 can directly activate the IL-5 and IL-13 promoters and induce chromatin remodeling at the il4 locus.
IL-13 Binding (activate) of GATA-3
1) Confidence 0.01 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526596 Disease Relevance 0.12 Pain Relevance 0.15

General Comments

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