INT194865

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (SIGMAR1) nuclear envelope (SIGMAR1) aging (IL1B)
endoplasmic reticulum (SIGMAR1) cell-cell signaling (IL1B) cytosol (IL1B)
SIGMAR1 (Homo sapiens)
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 10 97.24 Very High Very High Very High
Osteoarthritis 190 95.40 Very High Very High Very High
cytokine 15 90.36 High High
Inflammation 18 21.84 Low Low
Arthritis 3 6.56 Low Low
Pain 16 5.00 Very Low Very Low Very Low
imagery 11 5.00 Very Low Very Low Very Low
licofelone 3 5.00 Very Low Very Low Very Low
medial meniscus tear 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 1 99.92 Very High Very High Very High
Rheumatoid Arthritis 10 97.24 Very High Very High Very High
Osteoarthritis 190 95.40 Very High Very High Very High
Stress 1 54.88 Quite High
Osteophyte 4 25.84 Quite Low
INFLAMMATION 19 21.84 Low Low
Arthritis 6 6.56 Low Low
Disease 36 5.00 Very Low Very Low Very Low
Pain 15 5.00 Very Low Very Low Very Low
Injury 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-1 activity is mediated by its binding only to type I receptor; type II receptor did not mediate IL-1 activity.
type I receptor Binding (binding) of Positive_regulation (mediated) of IL-1
1) Confidence 0.01 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526599 Disease Relevance 0.62 Pain Relevance 0.35

General Comments

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