INT194875

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.39
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAPK14) nucleoplasm (MAPK14) signal transduction (MAPK14)
nucleus (MAPK14) response to stress (MAPK14) cytoplasm (MAPK14)
Anatomy Link Frequency
cartilage 3
chondrocyte 1
MAPK14 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 36 92.36 High High
Osteoarthritis 380 89.64 High High
Arthritis 6 85.28 High High
rheumatoid arthritis 20 83.76 Quite High
Inflammatory mediators 2 66.48 Quite High
cytokine 30 21.68 Low Low
Pain 32 5.00 Very Low Very Low Very Low
imagery 22 5.00 Very Low Very Low Very Low
licofelone 6 5.00 Very Low Very Low Very Low
medial meniscus tear 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 38 92.36 High High
Osteoarthritis 380 89.64 High High
Arthritis 12 85.28 High High
Rheumatoid Arthritis 20 83.76 Quite High
Cancer 8 81.92 Quite High
Necrosis 8 81.36 Quite High
Osteophyte 8 71.36 Quite High
Stress 2 56.68 Quite High
Disease 72 36.88 Quite Low
Toxicity 2 31.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, p38 mitogen-activated protein kinase inhibitors were shown to blunt chondrocyte and cartilage proteoglycan synthesis in response to transforming growth factor-?
Regulation (blunt) of Negative_regulation (inhibitors) of p38 in cartilage
1) Confidence 0.04 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526599 Disease Relevance 1.20 Pain Relevance 0.45
However, p38 mitogen-activated protein kinase inhibitors were shown to blunt chondrocyte and cartilage proteoglycan synthesis in response to transforming growth factor-?
Regulation (blunt) of in chondrocyte Negative_regulation (inhibitors) of p38 in cartilage
2) Confidence 0.01 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526599 Disease Relevance 1.20 Pain Relevance 0.45

General Comments

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