INT194903

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Context Info
Confidence 0.37
First Reported 2004
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 12
Total Number 12
Disease Relevance 5.06
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Cd34) cell adhesion (Cd34) cytoplasm (Cd34)
Anatomy Link Frequency
blood 2
superior 1
vessels 1
bone marrow 1
Cd34 (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 4 99.80 Very High Very High Very High
rheumatoid arthritis 79 96.16 Very High Very High Very High
cytokine 78 94.48 High High
metalloproteinase 22 70.80 Quite High
anesthesia 11 61.84 Quite High
cva 2 53.04 Quite High
ischemia 47 50.00 Quite Low
chemokine 12 38.00 Quite Low
Inflammation 26 14.32 Low Low
Osteoarthritis 17 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 80 99.00 Very High Very High Very High
Cancer 281 98.72 Very High Very High Very High
Rheumatoid Arthritis 81 96.16 Very High Very High Very High
Metastasis 71 90.72 High High
Adhesions 5 72.48 Quite High
Severe Combined Immunodeficiency 16 70.16 Quite High
Malignant Neoplastic Disease 19 69.16 Quite High
Obesity 41 65.60 Quite High
Wound Healing 66 64.36 Quite High
Aging 4 61.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
They showed that a lower blood withdrawal rate was associated with a higher MNC yield and CD34+ cell yield (Suzuya et al., 2005; Wang et al., 2008).
CD34 Binding (associated) of in blood associated with withdrawal
1) Confidence 0.37 Published 2010 Journal Transfusion Medicine (Oxford, England) Section Body Doc Link PMC2871169 Disease Relevance 0.13 Pain Relevance 0.08
Although eight donors and four donors attained PB and BM CD34+ cell count of <2× 106 kg?
CD34 Binding (count) of
2) Confidence 0.37 Published 2010 Journal Transfusion Medicine (Oxford, England) Section Body Doc Link PMC2871169 Disease Relevance 0.70 Pain Relevance 0
The mean CD34+ cell count, cell yield and recipient cell dose from BM after management were 374·9 × 106cells, 468·0 × 106 L?
CD34 Binding (management) of
3) Confidence 0.37 Published 2010 Journal Transfusion Medicine (Oxford, England) Section Body Doc Link PMC2871169 Disease Relevance 0.58 Pain Relevance 0
Figure 5A shows the engraftment of huCD45 and huCD34 in the bone marrow of individual animals revealing the superior potential of the zVADfmk/zLLYfmk expanded graft compared to the standard cytokine expanded graft (p?
huCD34 Binding (engraftment) of in superior associated with cytokine
4) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923186 Disease Relevance 0.07 Pain Relevance 0.05
They were also immunoreactive for CD34 (Fig. 4).


CD34 Binding (immunoreactive) of
5) Confidence 0.28 Published 2004 Journal Journal of Korean Medical Science Section Body Doc Link PMC2822305 Disease Relevance 0.67 Pain Relevance 0.03
As shown in Figure 4A-L, the numbers of blood and lymphatic microvessels were determined by a double immunohistochemical staining with the blood vessel endothelial cell marker CD34 and lymphatic vessel endothelial marker Lyve-1.
CD34 Spec (determined) Binding (staining) of in blood
6) Confidence 0.23 Published 2010 Journal BMC Med Section Body Doc Link PMC2989928 Disease Relevance 0.98 Pain Relevance 0
The cells were then trypsinized for 1 minute, centrifuged, washed with PBS, fixed in 4% paraformaldehyde for 0.5 hour at room temperature, washed and blocked in 2%FCS for 0.5 hour at room temperature with agitation. 1.5×105cells were then incubated with each of the following conjugated monoclonal antibodies: Tie-2, Flk-1, CD34, c-Kit, Thy-1, Sca-1 (PharMingen, San Diego, CA) for 90 mins at room temperature.
CD34 Binding (temperature) of
7) Confidence 0.22 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762397 Disease Relevance 0.30 Pain Relevance 0.06
Characterization of the cells for their immunophenotypic markers by fluorescent-activated cell sorting (FACS) showed that they were negative for cell lineage markers CD45, CD14, CD34, CD19, CD3, Flk-1 and positive for typical MSC surface proteins Sca-1, CD105, CD29, CD90, CD73 and CD44 (Table 1).
CD34 Neg (negative) Binding (lineage) of
8) Confidence 0.18 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2270908 Disease Relevance 0.30 Pain Relevance 0
Characterization of the cells for their immunophenotypic markers by fluorescent-activated cell sorting (FACS) showed that they were negative for cell lineage markers CD45, CD14, CD34, CD19, CD3, Flk-1 and positive for typical MSC surface proteins Sca-1, CD105, CD29, CD90, CD73 and CD44 (Table 1).
CD34 Binding (negative) of
9) Confidence 0.18 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2270908 Disease Relevance 0.30 Pain Relevance 0
These cells express CD29, CD105 and are negative for CD34 and CD45.
CD34 Binding (negative) of
10) Confidence 0.17 Published 2008 Journal J Transl Med Section Body Doc Link PMC2533293 Disease Relevance 0 Pain Relevance 0
To evaluate pericyte coverage index, all CD34-positive vessels associated with ?
CD34 Binding (index) of in vessels
11) Confidence 0.14 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2894797 Disease Relevance 0.47 Pain Relevance 0
As shown in Figure 8, treatment of bone marrow CD34+ cells with siRNA for NF?
CD34 Binding (treatment) of in bone marrow
12) Confidence 0.08 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526601 Disease Relevance 0.55 Pain Relevance 0.34

General Comments

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