INT19491

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Context Info
Confidence 0.75
First Reported 1991
Last Reported 2011
Negated 8
Speculated 0
Reported most in Body
Documents 44
Total Number 46
Disease Relevance 28.80
Pain Relevance 3.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD19)
Anatomy Link Frequency
B cell 14
lymphocytes 3
PCs 2
blood 2
adipocytes 2
CD19 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 98 98.72 Very High Very High Very High
depression 16 97.56 Very High Very High Very High
Inflammation 218 96.64 Very High Very High Very High
Central nervous system 63 96.00 Very High Very High Very High
Acupuncture 56 94.40 High High
intrathecal 29 93.44 High High
methotrexate 4 92.48 High High
Patient controlled epidural analgesia 1 91.80 High High
Morphine 1 89.64 High High
analgesia 6 89.00 High High
Disease Link Frequency Relevance Heat
Diffuse Large B-cell Lymphoma 173 99.98 Very High Very High Very High
Follicular Lymphoma 67 99.98 Very High Very High Very High
Lymphatic System Cancer 446 99.76 Very High Very High Very High
Cancer 314 99.76 Very High Very High Very High
B-cell Lymphoma 84 99.76 Very High Very High Very High
Histiocytic Sarcoma 33 99.14 Very High Very High Very High
Hematological Disease 4 99.08 Very High Very High Very High
Disorders Of Creatine Metabolism 4 98.94 Very High Very High Very High
Mantle-cell Lymphoma 99 98.84 Very High Very High Very High
Chronic Fatigue Syndrome 456 98.62 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lymphocytes in patients with stable and unstable angina showed a similar percent expression of CD2/CD19 and CD3/HLA-DR antigens, with no difference between aortic and coronary sinus blood.
Gene_expression (expression) of CD19 in blood
1) Confidence 0.75 Published 1995 Journal J. Am. Coll. Cardiol. Section Body Doc Link 7594025 Disease Relevance 0 Pain Relevance 0
The secondary outcome measures were in vivo changes in lymphocyte subsets [Mature T Cells (CD3+), B Cells (CD19+), Helper T cells (CD3+CD4+), Cytotoxic T Cells (CD3+CD8+), Natural Killer (NK) Cells (CD3-CD16+and/orCD56+)], phagocytosis of granulocytes and monocytes, natural killer cell cytotoxicity and cyclooxygenase-2 (COX-2) expression.
Gene_expression (expression) of CD19 in lymphocyte
2) Confidence 0.75 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC2888736 Disease Relevance 0.39 Pain Relevance 0.04
These cells expressed CD19, CD20, HLA-DR antigens.
Gene_expression (expressed) of CD19
3) Confidence 0.72 Published 1991 Journal Rinsho Ketsueki Section Abstract Doc Link 2067086 Disease Relevance 0.73 Pain Relevance 0.06
TNFRSF17 is selected as a candidate susceptibility gene to IBD pathogenesis by our cDNA microarray analysis, and we showed the specific expression of TNFRSF17 in resting and activated CD19(+) cells obtained from human blood.
Gene_expression (resting) of CD19 in blood associated with inflammatory bowel disease
4) Confidence 0.65 Published 2010 Journal Mol. Cells Section Abstract Doc Link 20016944 Disease Relevance 0.45 Pain Relevance 0.20
While the vast majority of all CSF B cells were CD19+CD138?
Gene_expression (majority) of CD19 in B cells
5) Confidence 0.61 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2438478 Disease Relevance 0.53 Pain Relevance 0.14
Flow cytometric analysis was used for monitoring the expression of CD3+, CD4+, CD8+, CD19+, CD16+ & CD56+ antigens on peripheral blood lymphocytes (PBL).
Gene_expression (expression) of CD19 in lymphocytes
6) Confidence 0.58 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC2888736 Disease Relevance 0 Pain Relevance 0
Immunophenotypic analysis demonstrated that the leukemic B cells were positive for CD19, CD20, and HLA-DR, but CD5 was difficult to detect.
Gene_expression (positive) of CD19 in B cells
7) Confidence 0.58 Published 2003 Journal Leuk. Lymphoma Section Abstract Doc Link 12916878 Disease Relevance 0.76 Pain Relevance 0.39
The lymphoma cells were positive for CD2, CD3, CD5, CD8, and T-cell receptor (TCR) beta F1, but negative for CD4, CD19, CD20, CD103, and CD56.
Neg (negative) Gene_expression (negative) of CD19 in T-cell associated with lymphatic system cancer
8) Confidence 0.56 Published 2003 Journal J. Gastroenterol. Section Abstract Doc Link 12743779 Disease Relevance 0.78 Pain Relevance 0.10
The majority of these B cells showed the expression pattern of mature B cells (phenotype: CD19+CD138?)
Gene_expression (expression) of CD19 in mature B cells
9) Confidence 0.55 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2438478 Disease Relevance 1.18 Pain Relevance 0.34
Correlation of CD19 counts and AQP4-Ab levels under treatment with rituximab
Gene_expression (counts) of CD19
10) Confidence 0.53 Published 2008 Journal Brain Section Body Doc Link PMC2577801 Disease Relevance 0.25 Pain Relevance 0.04
However, B cells remained detectable in all patients not treated with rituximab, with no correlation between CD19 counts and AQP4-Ab serum values.
Gene_expression (counts) of CD19 in B cells
11) Confidence 0.53 Published 2008 Journal Brain Section Body Doc Link PMC2577801 Disease Relevance 0.50 Pain Relevance 0
No correlation between CD19 cell count and AQP4-Ab values was found in those patients not treated with rituximab (data not shown).
Gene_expression (values) of CD19
12) Confidence 0.53 Published 2008 Journal Brain Section Body Doc Link PMC2577801 Disease Relevance 0.62 Pain Relevance 0
The DLBCL expressed CD19, CD20, CD79a, CD5, CD10, CD23, CD38, CD117, bcl-2, and bcl-6, with monotypic expression of immunoglobulin kappa light chain.
Gene_expression (expressed) of CD19 associated with diffuse large b-cell lymphoma
13) Confidence 0.53 Published 2005 Journal Am. J. Clin. Pathol. Section Abstract Doc Link 15842045 Disease Relevance 0.76 Pain Relevance 0.11
First, the increase of CD2+, CD4+, CD8+, CD11b+, CD16+, CD19+ and CD56+ cell counts as well as the levels of IL-1?
Gene_expression (cell) of CD19
14) Confidence 0.51 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2176150 Disease Relevance 0 Pain Relevance 0.39
Circulating cytokines, C-reactive protein (CRP), cortisol, and cell-surface receptor expression of immune cells (cluster of differentiation [CD]14, human leukocyte antigen-DR, CD86, CD71, CD3, CD4, CD8, CD16, and CD19) were measured perioperatively to characterize immunological functions.
Gene_expression (expression) of CD19 in CD86 associated with cytokine
15) Confidence 0.49 Published 2004 Journal Anesth. Analg. Section Abstract Doc Link 15041604 Disease Relevance 0.48 Pain Relevance 0.68
Results in Table 3 show that the median expression of the CD19+ B cell up-regulated gene set was significantly lower in CFS (p = 0.01) and ISF (p = 0.05) subjects when compared to the NF group.
Gene_expression (expression) of CD19 in B cell associated with chronic fatigue syndrome and fatigue
16) Confidence 0.48 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2569951 Disease Relevance 0.93 Pain Relevance 0
Expression of this CD19+ B cell up-regulated gene set also discriminated ISF from controls at 0.05 confidence level.
Gene_expression (Expression) of CD19 in B cell associated with fatigue
17) Confidence 0.48 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2569951 Disease Relevance 0.59 Pain Relevance 0.03
The DLBCL expressed CD19, CD20, CD79a, CD5, CD10, CD23, CD38, CD117, bcl-2, and bcl-6, with monotypic expression of immunoglobulin kappa light chain.
Gene_expression (expression) of CD19 associated with diffuse large b-cell lymphoma
18) Confidence 0.46 Published 2005 Journal Am. J. Clin. Pathol. Section Abstract Doc Link 15842045 Disease Relevance 0.76 Pain Relevance 0.11
These findings together with our observations of depressed CD19+ gene expression and altered association between up and down-regulated B cell functions would suggest that the function of these cells might be compromised in CFS subjects.
Gene_expression (expression) of CD19 in B cell associated with chronic fatigue syndrome
19) Confidence 0.41 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2569951 Disease Relevance 0.68 Pain Relevance 0.05
The CD14+ monocyte set also shared significant co-expression with the CD19+ B cell gene sets.
Gene_expression (expression) of CD19 in B cell
20) Confidence 0.41 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2569951 Disease Relevance 0.37 Pain Relevance 0.14

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