INT194971

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Context Info
Confidence 0.14
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.81
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Alox5) nuclear envelope (Alox5) oxidoreductase activity (Alox5)
nucleus (Alox5) cytoplasm (Alox5)
Alox5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 22 79.04 Quite High
Bioavailability 4 66.12 Quite High
ischemia 21 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 97.32 Very High Very High Very High
Stroke 17 96.00 Very High Very High Very High
INFLAMMATION 30 79.04 Quite High
Injury 22 75.24 Quite High
Brain Hemorrhage 8 55.84 Quite High
Aneurism 1 34.68 Quite Low
Cv Unclassified Under Development 13 5.00 Very Low Very Low Very Low
Infarction 8 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 7 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study demonstrates the protective effect of 5-LOX inhibitors when administered either prior to ischemic insult or at reperfusion in a rat model of experimental stroke.
Negative_regulation (effect) of Negative_regulation (inhibitors) of 5-LOX associated with stroke
1) Confidence 0.14 Published 2006 Journal J Neuroinflammation Section Body Doc Link PMC1526713 Disease Relevance 0.81 Pain Relevance 0.13

General Comments

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