INT195009

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Cast) nucleus (Cast) cell cycle (Cast)
cytoplasm (Cast)
Cast (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 144 98.06 Very High Very High Very High
nMDA receptor 6 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
excitatory amino acid 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Glutamate receptor 1 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 80 86.44 High High
Apoptosis 97 86.00 High High
Neurodegenerative Disease 11 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low
Aging 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Parkinson's Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment with glutamate induced accumulation of both 145 KDa and 120 KDa BDPs in primary cortical cells, which could be reduced with both calpain inhibitor (ALLN) and caspase-3 inhibitor (z-DEVD-fmk).
Negative_regulation (inhibitor) of Gene_expression (reduced) of calpain inhibitor associated with glutamate
1) Confidence 0.04 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1526740 Disease Relevance 0.87 Pain Relevance 0.26

General Comments

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