INT195053

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PTHLH, CPOX) mitochondrion (CPOX) small molecule metabolic process (CPOX)
Golgi apparatus (PTHLH) intracellular (PTHLH) cell-cell signaling (PTHLH)
Anatomy Link Frequency
fibroblast 2
PTHLH (Homo sapiens)
CPOX (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 25 50.00 Quite Low
Pain 12 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
visual analogue scale 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Phosphate Metabolism Disorders 55 99.16 Very High Very High Very High
Disorders Of Creatine Metabolism 1 20.32 Low Low
Pain 12 5.00 Very Low Very Low Very Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Fatigue 5 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 2 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Muscle Weakness 1 5.00 Very Low Very Low Very Low
Milium 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In normal fibroblasts, the addition of PLP did not alter COX-2 gene expression, whereas in the two HP fibroblast types, a slight increase of COX-2 production was noted (3-way ANOVA, p = 0.71) (figure 5).
PLP Neg (not) Regulation (alter) of Gene_expression (expression) of COX in fibroblast associated with phosphate metabolism disorders
1) Confidence 0.03 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1533806 Disease Relevance 0.71 Pain Relevance 0

General Comments

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