INT195204

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Context Info
Confidence 0.25
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.37
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tenc1)
Anatomy Link Frequency
thickening 2
Tenc1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 5 97.38 Very High Very High Very High
anesthesia 4 8.88 Low Low
Hippocampus 22 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
Nerve growth factor 4 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
nMDA receptor 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Normal Pressure Hydrocephalus 48 100.00 Very High Very High Very High
Aging 3 100.00 Very High Very High Very High
Targeted Disruption 25 99.78 Very High Very High Very High
Disease 220 99.68 Very High Very High Very High
Fibrosis 5 97.38 Very High Very High Very High
Alzheimer's Dementia 49 96.48 Very High Very High Very High
Amyloid Plaque 15 79.56 Quite High
Syndrome 8 76.96 Quite High
Hydrocephalus 9 56.32 Quite High
Immunization 7 37.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
catabolism, with the NEP and sNEP conditions reducing A?
Regulation (with) of Gene_expression (conditions) of NEP
1) Confidence 0.25 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1952204 Disease Relevance 0 Pain Relevance 0
Age-related accumulations of amyloid in the choroid plexus and meninges, fibrosis, thickening of the basement membrane, and senescent changes in the choroidal epithelium and choroidal vasculature probably play a role both in decreased CSF production and decreased CSF absorption in normal aging, in NPH and in AD [1,12,15,16].
Regulation (role) of Gene_expression (production) of NPH in thickening associated with fibrosis, normal pressure hydrocephalus, aging, alzheimer's dementia and disease
2) Confidence 0.20 Published 2006 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC1538629 Disease Relevance 1.63 Pain Relevance 0.09
A study using AD transgenic mice that had an over expression of IDE or NEP demonstrated a significant reduction in A?
Regulation (had) of Gene_expression (expression) of NEP associated with targeted disruption and disease
3) Confidence 0.11 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2536544 Disease Relevance 0.74 Pain Relevance 0

General Comments

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