INT195206

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Context Info
Confidence 0.41
First Reported 2006
Last Reported 2011
Negated 0
Speculated 2
Reported most in Body
Documents 15
Total Number 17
Disease Relevance 21.30
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
nasopharynx 1
Skin 1
pigmentation 1
cervix 1
Basal cell 1
BCC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 3 100.00 Very High Very High Very High
spinal inflammation 3 88.16 High High
Bile 54 74.40 Quite High
Kinase C 1 74.24 Quite High
Inflammation 4 70.16 Quite High
cryotherapy 34 60.48 Quite High
Pain 21 56.40 Quite High
imagery 8 16.32 Low Low
cytokine 2 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 901 100.00 Very High Very High Very High
Cancer 182 99.52 Very High Very High Very High
Weight Gain 50 99.40 Very High Very High Very High
Obesity 135 98.84 Very High Very High Very High
Fibrosis 21 97.84 Very High Very High Very High
Overweight 15 97.68 Very High Very High Very High
Malignant Neoplastic Disease 23 97.64 Very High Very High Very High
Disease 34 97.52 Very High Very High Very High
Apoptosis 12 96.80 Very High Very High Very High
Thinness 25 96.68 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Strengths of this study include its large population sample with a high participation rate as well as its prospective design, and the ability to assess a large number of other risk factors as possible confounders of the association between anthropometric measures and BCC.
BCC Binding (association) of associated with skin cancer
1) Confidence 0.41 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1539017 Disease Relevance 0.97 Pain Relevance 0
Although the current study was also not designed specifically to examine the association between anthropometric measures and BCC, information on a large number of other risk factors, including phenotypic characteristics and sun exposure history, was collected and these risk factors were assessed as possible confounders in the relationship between BCC and anthropometric measures.
BCC Spec (examine) Binding (association) of associated with sunburn and skin cancer
2) Confidence 0.32 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1539017 Disease Relevance 1.14 Pain Relevance 0
Basal cell carcinomas were the most frequent tumors arising on chronic radiodermatitis.3 The radiogenic BCCs tend to be multiple and they manifest as conventional nodular BCC, superficial BCC and rarely, fibroepithelioma Pinkus and keloidal types.7 Also, linear BCC can develop rarely in the irradiated areas.19
BCC Binding (linear) of in Basal cell associated with radiodermatitis, cancer, skin cancer and basal cell carcinoma
3) Confidence 0.31 Published 2008 Journal Indian Journal of Dermatology Section Body Doc Link PMC2763736 Disease Relevance 1.87 Pain Relevance 0
With respect to short-term weight change and development of BCC 1992–1996, weight gain showed a suggestive positive association with BCC for women (Table 2), but the point estimates were not statistically significant.
BCC Binding (association) of associated with weight gain and skin cancer
4) Confidence 0.31 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1539017 Disease Relevance 1.57 Pain Relevance 0
Adjusted PPRs of prevalent BCC associated with anthropometric measures are shown in Table 1.
BCC Binding (associated) of associated with skin cancer
5) Confidence 0.31 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1539017 Disease Relevance 1.78 Pain Relevance 0
Sahl et al (1995) in a small case-control study based on 46 cases reported a positive association between weight and BCC, whilst Milan et al (2003) in a nested case-control study of disease-discordant same-sex twin pairs based on 333 cases of BCC, found no relationship between BMI and risk of BCC.
BCC Binding (association) of associated with disease and skin cancer
6) Confidence 0.31 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1539017 Disease Relevance 1.06 Pain Relevance 0
Karagas suggests that exposure to therapeutic radiation is associated with BCC but not with SCC.1 These neoplasms usually occurs after radiation therapy for treatment of tinea capitis, hypertrophic tonsillitis4 acne vulgaris,14 atopic dermatitis and hyperthyroidism4 and rarely following cancer of cervix and nasopharynx,12 neck lymph node tuberculosis,5 medulloblastoma,13 ankylosing spondylitis,14 hemangioma1516 and hirsutism.7 A recent report suggested an increased risk of nonmelanoma skin cancer among the latest Japanese atomic bomb survivors.1
BCC Binding (associated) of in cervix associated with hirsutism, spinal inflammation, cervical cancer, tinea, acne, medulloblastoma, eczema, skin cancer, cancer and lymph node tuberculosis
7) Confidence 0.30 Published 2008 Journal Indian Journal of Dermatology Section Body Doc Link PMC2763736 Disease Relevance 2.35 Pain Relevance 0.09
We have to recognize BCC and its different histologic subtypes, as well as areas in which these might occur.
BCC Spec (might) Binding (recognize) of associated with skin cancer
8) Confidence 0.21 Published 2011 Journal Journal of Skin Cancer Section Body Doc Link PMC3010650 Disease Relevance 2.18 Pain Relevance 0.06
BCC is associated with mutations in components of the hedgehog signaling pathway [75].
BCC Binding (associated) of associated with skin cancer
9) Confidence 0.21 Published 2011 Journal Journal of Skin Cancer Section Body Doc Link PMC3010650 Disease Relevance 0.86 Pain Relevance 0
Curettage and cautery is one of the commonest tools used by dermatologists in management of BCC.
BCC Binding (management) of associated with skin cancer
10) Confidence 0.15 Published 2011 Journal Journal of Skin Cancer Section Body Doc Link PMC2989864 Disease Relevance 1.92 Pain Relevance 0.06
Skin type is associated with melanocortin 1 receptor (MC1R) polymorphisms and an independent risk factor for BCC.
BCC Binding (associated) of in Skin associated with melanocortin 1 receptor and skin cancer
11) Confidence 0.15 Published 2011 Journal Journal of Skin Cancer Section Body Doc Link PMC2989864 Disease Relevance 1.09 Pain Relevance 0.10
Karagas suggests that exposure to therapeutic radiation is associated with BCC but not with SCC.1 These neoplasms usually occurs after radiation therapy for treatment of tinea capitis, hypertrophic tonsillitis4 acne vulgaris,14 atopic dermatitis and hyperthyroidism4 and rarely following cancer of cervix and nasopharynx,12 neck lymph node tuberculosis,5 medulloblastoma,13 ankylosing spondylitis,14 hemangioma1516 and hirsutism.7 A recent report suggested an increased risk of nonmelanoma skin cancer among the latest Japanese atomic bomb survivors.1
BCC Binding (associated) of in nasopharynx associated with hirsutism, spinal inflammation, cervical cancer, tinea, acne, medulloblastoma, eczema, skin cancer, cancer and lymph node tuberculosis
12) Confidence 0.10 Published 2008 Journal Indian Journal of Dermatology Section Body Doc Link PMC2763736 Disease Relevance 2.35 Pain Relevance 0.09
We have conducted an univariate association between each liable factors and the BCC occurrences with the ?
BCC Binding (association) of
13) Confidence 0.07 Published 2010 Journal BMC Surg Section Body Doc Link PMC2867769 Disease Relevance 0.42 Pain Relevance 0.04
When it is soft, the risk to find BCC is very low about 0.6%, whereas patients with thick (fibrotic or calcified) pericyst increase their risk to have BCC to 33.5%.
BCC Binding (find) of associated with fibrosis
14) Confidence 0.05 Published 2010 Journal BMC Surg Section Body Doc Link PMC2867769 Disease Relevance 0.36 Pain Relevance 0.12
We have conducted a univariate association between each liable factors and the BCC occurrences with univariate binary logistic regression analysis.
BCC Binding (association) of
15) Confidence 0.05 Published 2010 Journal BMC Surg Section Body Doc Link PMC2867769 Disease Relevance 0.25 Pain Relevance 0.03
From a clinical point of view, the most convincing yet rather confusing—due to several contradicting results—research focuses on the association of BCC with pigmentation and DNA repair genes, respectively.
BCC Binding (association) of in pigmentation associated with skin cancer
16) Confidence 0.01 Published 2011 Journal Journal of Skin Cancer Section Body Doc Link PMC3021865 Disease Relevance 1.13 Pain Relevance 0
Both CRY proteins inhibit the transcription of both crys and pers by binding to the BCC.
BCC Binding (binding) of
17) Confidence 0.01 Published 2007 Journal PLoS Computational Biology Section Body Doc Link PMC2134962 Disease Relevance 0 Pain Relevance 0.04

General Comments

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