INT19542

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Context Info
Confidence 0.50
First Reported 1991
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.52
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tbxa2r) plasma membrane (Tbxa2r) signal transducer activity (Tbxa2r)
Anatomy Link Frequency
plaque 2
saliva 2
Tbxa2r (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 96.04 Very High Very High Very High
Migraine 3 95.20 Very High Very High Very High
antagonist 3 94.32 High High
headache 1 75.00 Quite High
aspirin 29 49.36 Quite Low
agonist 1 42.56 Quite Low
Serotonin 1 17.52 Low Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 96.04 Very High Very High Very High
Migraine With Aura 3 95.20 Very High Very High Very High
Atherosclerotic Plaque 2 95.00 High High
Headache 1 75.00 Quite High
Diabetes Mellitus 32 50.00 Quite Low
Cardiovascular Disease 4 12.48 Low Low
Peripheral Arterial Disease 20 5.00 Very Low Very Low Very Low
Atherosclerosis 9 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In relation to the control group we observed a significant decrease in the plasma levels of PGI2 together with a sharp increase in TXA2 in saliva.
Negative_regulation (decrease) of Positive_regulation (increase) of TXA2 in saliva
1) Confidence 0.50 Published 1991 Journal Headache Section Abstract Doc Link 2071393 Disease Relevance 0.33 Pain Relevance 0.38
The reduction of circulating platelet-derived TxA2 levels induced by picotamide not only inhibits platelet aggregation, but also has important consequences for the inflammatory processes of atherosclerotic plaque.
Negative_regulation (reduction) of Positive_regulation (induced) of TxA2 in plaque associated with atherosclerotic plaque and inflammation
2) Confidence 0.26 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994050 Disease Relevance 0.19 Pain Relevance 0.05

General Comments

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