INT195420

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Context Info
Confidence 0.67
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.07
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (TPM1) cytosol (TPM1) cytoskeleton (TPM1)
cytoskeleton organization (TPM1) cytoplasm (TPM1)
TPM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 27 90.88 High High
imagery 21 5.00 Very Low Very Low Very Low
Action potential 11 5.00 Very Low Very Low Very Low
isoflurane 5 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nervous System Malformation 1 74.44 Quite High
Hypersensitivity 21 43.44 Quite Low
Repression 1 32.20 Quite Low
Teratoma 10 5.00 Very Low Very Low Very Low
Myocardial Infarction 8 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-actin, myosin, and tropomyosin were increased 10.2- to 117-fold.
Positive_regulation (increased) of tropomyosin
1) Confidence 0.67 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2248711 Disease Relevance 0 Pain Relevance 0.12
All methods were able to correctly assign the held-out allergens (data not shown), but as demonstrated for tropomyosins and parvalbumins DFLAP was the only method to predict non-allergen protein family members outstandingly well (Figure 4).
Positive_regulation (demonstrated) of tropomyosin
2) Confidence 0.49 Published 2006 Journal Nucleic Acids Research Section Body Doc Link PMC1540723 Disease Relevance 0 Pain Relevance 0
At the same time, we observe substantial increases in expression of 1,012 genes, including cardiac structural genes such as tropomyosin 1 and 2 (TPM1, 2, ?
Positive_regulation (increases) of tropomyosin 1
3) Confidence 0.45 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2565131 Disease Relevance 0.07 Pain Relevance 0

General Comments

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