INT195424

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SNRNP70) small molecule metabolic process (GBE1) transferase activity, transferring glycosyl groups (GBE1)
carbohydrate metabolic process (GBE1) cytosol (GBE1) generation of precursor metabolites and energy (GBE1)
SNRNP70 (Homo sapiens)
GBE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 4 90.96 High High
Pain 88 78.48 Quite High
Acute pain 3 67.44 Quite High
monoamine 21 50.00 Quite Low
Neurotransmitter 20 50.00 Quite Low
Serotonin 5 41.84 Quite Low
Analgesic 5 30.68 Quite Low
visual analogue scale 4 5.00 Very Low Very Low Very Low
Catecholamine 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 92 78.48 Quite High
Disease 2 72.48 Quite High
Nociception 3 5.00 Very Low Very Low Very Low
Impacted Tooth 1 5.00 Very Low Very Low Very Low
Aggression 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Neck Pain 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Temporomandibular Joint Disorders 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mis-sense SNP 11 (rs4680) of COMT markedly reduces enzyme activity to about 20–40% of wild-type levels [18-20].
SNP 11 Negative_regulation (reduces) of enzyme
1) Confidence 0.00 Published 2006 Journal Mol Pain Section Body Doc Link PMC1543620 Disease Relevance 0.22 Pain Relevance 0.19

General Comments

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