INT195453

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Context Info
Confidence 0.42
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 4.41
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SAT1) small molecule metabolic process (SAT1) intracellular (SAT1)
transferase activity, transferring acyl groups (SAT1) cellular nitrogen compound metabolic process (SAT1) cytoplasm (SAT1)
Anatomy Link Frequency
plasma 2
SAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Endocannabinoid 70 99.68 Very High Very High Very High
Potency 2 81.20 Quite High
Cannabinoid receptor 14 77.76 Quite High
Inflammatory response 3 60.08 Quite High
agonist 4 58.20 Quite High
corticosteroid 1 57.56 Quite High
Inflammation 45 50.00 Quite Low
cytokine 16 7.84 Low Low
alcohol 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 503 100.00 Very High Very High Very High
Colorectal Cancer 23 97.56 Very High Very High Very High
Adhesions 5 95.04 Very High Very High Very High
Diabetes Mellitus 70 94.96 High High
Endometriosis (extended) 5 88.68 High High
Injury 30 82.24 Quite High
Lung Injury 18 82.16 Quite High
Colon Cancer 3 80.12 Quite High
Adenocarcinoma 2 64.20 Quite High
INFLAMMATION 43 59.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
restored the SSAT promoter activity, and an activated PPAR?
Negative_regulation (restored) of Gene_expression (activity) of SSAT promoter
1) Confidence 0.42 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1543652 Disease Relevance 0.48 Pain Relevance 0
The average Sat PC pool for the lambs with < 5 ?
Negative_regulation (average) of Gene_expression (pool) of Sat PC
2) Confidence 0.11 Published 2010 Journal Respir Res Section Body Doc Link PMC2978154 Disease Relevance 0.37 Pain Relevance 0.06
However, in viscerally obese men, only increased plasma 2-AG levels correlated with decreased FAAH mRNA expression in the SAT [10].
Negative_regulation (decreased) of Gene_expression (expression) of SAT in plasma associated with obesity
3) Confidence 0.11 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2868848 Disease Relevance 1.38 Pain Relevance 0.17
In fact, whilst the SAT levels of the endocannabinoid AEA and of the PPAR?
Negative_regulation (whilst) of Gene_expression (levels) of SAT associated with endocannabinoid and obesity
4) Confidence 0.11 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2868848 Disease Relevance 1.02 Pain Relevance 0.31
The 20 genes that showed >10-fold higher expression in SAT are highly enriched in homeobox transcription factors (HOXA9, HOXA10, HOXC8, HOXC9, IRX2, and IRX5).
Negative_regulation (enriched) of Gene_expression (expression) of SAT associated with obesity
5) Confidence 0.06 Published 2010 Journal BMC Med Genomics Section Body Doc Link PMC2925326 Disease Relevance 1.17 Pain Relevance 0

General Comments

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