INT195467

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Context Info
Confidence 0.45
First Reported 2004
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.57
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (THPO) extracellular space (THPO) extracellular region (THPO)
Anatomy Link Frequency
blood 1
liver 1
platelet 1
THPO (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 2 57.04 Quite High
fibrosis 5 45.52 Quite Low
cerebral cortex 3 39.36 Quite Low
corticosteroid 2 11.84 Low Low
cva 28 11.04 Low Low
anesthesia 12 5.00 Very Low Very Low Very Low
sSRI 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Restless leg syndrome 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 4 99.52 Very High Very High Very High
Thrombocytopenia 47 99.46 Very High Very High Very High
Heart Rate Under Development 10 91.60 High High
Stroke 12 91.24 High High
Thrombosis Related Under Development 1 91.24 High High
Thrombosis 1 90.52 High High
Increased Venous Pressure Under Development 9 89.92 High High
Infection 4 69.56 Quite High
Hepatitis 2 69.08 Quite High
Overdose 2 61.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the placebo-controlled ITP studies there has been no difference reported in thrombotic events between treatment or placebo arms.15 A comparative analyses of eltrombopag and TPO on in vitro platelet function demonstrated that eltrombopag stimulates platelet signal transduction with little or no effect on overall platelet function, in contrast to TPO, which significantly primes platelet activation.41

Rebound thrombocytopenia

Neg (no) Spec (analyses) Regulation (difference) of TPO in platelet associated with thrombocytopenia
1) Confidence 0.45 Published 2010 Journal Drug Des Devel Ther Section Body Doc Link PMC2915538 Disease Relevance 0.85 Pain Relevance 0.06
Of these 11, 3 contained the requested information regarding the anti-TPO lab test.
Regulation (regarding) of anti-TPO
2) Confidence 0.10 Published 2004 Journal Journal of Medical Internet Research Section Body Doc Link PMC1550613 Disease Relevance 0.18 Pain Relevance 0
Despite the great variability affecting the NIRS signals, we found these common features in all the subjects we tested, provided that the BH duration was at least of 20 seconds.
Regulation (affecting) of NIRS
3) Confidence 0.01 Published 2006 Journal J Neuroengineering Rehabil Section Body Doc Link PMC1544341 Disease Relevance 0.15 Pain Relevance 0
Following liver trauma, CPP and CO as well as NIRS and TCD values decreased continuously.
Regulation (values) of NIRS in liver associated with injury
4) Confidence 0.00 Published 2006 Journal Crit Care Section Body Doc Link PMC1550846 Disease Relevance 0.19 Pain Relevance 0
Hemodynamic data, blood gases and NIRS values at the different experimental stages are presented in Table 1.
Regulation (values) of NIRS in blood
5) Confidence 0.00 Published 2006 Journal Crit Care Section Body Doc Link PMC1550846 Disease Relevance 0.20 Pain Relevance 0

General Comments

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