INT195575

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Context Info
Confidence 0.12
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.28
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Myo1f)
Anatomy Link Frequency
thick filament 1
Myo1f (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 10 57.84 Quite High
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Sciatic nerve 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nutritional Deficiencies 2 90.84 High High
Muscular Atrophy 18 76.56 Quite High
Cold Sores 18 56.08 Quite High
Herpes Virus Infection 4 50.00 Quite Low
Infection 28 5.00 Very Low Very Low Very Low
Ganglion Cysts 10 5.00 Very Low Very Low Very Low
Frailty 8 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Viral Infection 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During myofibrillogenesis, the developmental exchange of MyHC isoforms requires a myosin molecule to be released from its complex insertion into a sarcomeric thick filament, in order to be replaced by a subsequently expressed isoform.
Localization (released) of myosin in thick filament
1) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844429 Disease Relevance 0.22 Pain Relevance 0
These fractions from both sarcomeric (Fig. 3) and soluble myosin preparations (data not shown) contained MyHCemb and MLC, indicating the presence of multimeric myosin (?
Localization (presence) of myosin
2) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844429 Disease Relevance 0 Pain Relevance 0
We also did not detect any significant co-localization between capsids and myosin II (Figure S1).
Localization (localization) of myosin
3) Confidence 0.02 Published 2006 Journal PLoS Pathogens Section Body Doc Link PMC1550268 Disease Relevance 0.06 Pain Relevance 0.03

General Comments

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