INT195676

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Context Info
Confidence 0.19
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.63
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (KAT8) transcription factor binding (KAT8)
KAT8 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 42 87.92 High High
antagonist 2 70.04 Quite High
Inflammation 32 6.96 Low Low
cytokine 18 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
tissue acidosis 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Organ Failure 42 100.00 Very High Very High Very High
Cv General 2 Under Development 17 99.18 Very High Very High Very High
Pancreatitis 44 97.36 Very High Very High Very High
Injury 57 93.84 High High
Death 6 93.44 High High
Hemorrhagic Shock 46 92.32 High High
Hemorrhage 53 87.92 High High
Sepsis 15 87.76 High High
Disease 7 61.44 Quite High
Infection 3 60.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Low PC was found to precede MOF, and early APC/PC ratios were frequently high in MOF patients.
Negative_regulation (high) of MOF associated with multiple organ failure
1) Confidence 0.19 Published 2006 Journal Crit Care Section Body Doc Link PMC1550818 Disease Relevance 1.13 Pain Relevance 0
Despite improved resuscitation strategies for severely injured patients who present in shock, these transfusions are associated with development of MOF, increased ICU admissions and length of stay, increased hospital length of stay, and increased mortality.
Negative_regulation (development) of MOF associated with multiple organ failure and cv general 2 under development
2) Confidence 0.04 Published 2008 Journal Crit Care Section Body Doc Link PMC2575549 Disease Relevance 1.49 Pain Relevance 0.23

General Comments

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