INT19584

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Context Info
Confidence 0.56
First Reported 1990
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.82
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Ptafr) plasma membrane (Ptafr) nucleus (Ptafr)
signal transducer activity (Ptafr)
Anatomy Link Frequency
platelet 2
leukocyte 1
Ptafr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
corticosteroid 1 99.02 Very High Very High Very High
opiate 1 97.56 Very High Very High Very High
antagonist 1 97.28 Very High Very High Very High
Antihistamine 1 96.76 Very High Very High Very High
Calcium channel 1 96.12 Very High Very High Very High
tolerance 1 88.84 High High
fibrosis 2 82.72 Quite High
Dismenorea 1 81.12 Quite High
Paracetamol 1 79.76 Quite High
aspirin 1 71.68 Quite High
Disease Link Frequency Relevance Heat
Cancer 1 99.92 Very High Very High Very High
Necrosis 1 99.68 Very High Very High Very High
Adhesions 1 98.40 Very High Very High Very High
Injury 3 91.52 High High
Stomach Cancer 1 89.84 High High
Disease 1 89.76 High High
Enteropathy 1 88.56 High High
Constipation 1 87.20 High High
Dementia 1 86.80 High High
Endotoxemia 2 85.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The primary active constituents of the leaves include flavonoid glycosides and unique diterpenes known as ginkgolides; the latter are potent inhibitors of platelet activating factor.
Negative_regulation (inhibitors) of platelet activating factor in platelet
1) Confidence 0.56 Published 2001 Journal Altern Ther Health Med Section Abstract Doc Link 11565403 Disease Relevance 0.34 Pain Relevance 0.08
It inhibits platelet-activating factor and leukocyte adherence, and modulates adhesion molecule expression.
Negative_regulation (inhibits) of platelet-activating factor in leukocyte associated with adhesions
2) Confidence 0.13 Published 2001 Journal Pharmacotherapy Section Abstract Doc Link 11191738 Disease Relevance 1.04 Pain Relevance 0.19
The effects of corticosteroids, cyclooxygenase blockers, leukotriene blockers, platelet activating factor blockers, tumor necrosis factor blockers, oxygen radical scavengers, opiate antagonists, antihistamines, calcium channel blockers are detailed.
Negative_regulation (blockers) of platelet activating factor in platelet associated with necrosis, corticosteroid, cancer, calcium channel, antihistamine, antagonist and opiate
3) Confidence 0.05 Published 1990 Journal J. Vet. Intern. Med. Section Abstract Doc Link 2074555 Disease Relevance 0.44 Pain Relevance 0.34

General Comments

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