INT195858

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Context Info
Confidence 0.69
First Reported 2006
Last Reported 2006
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 9
Disease Relevance 1.33
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

immune system process (Ahr) cell morphogenesis (Ahr) DNA binding (Ahr)
response to stress (Ahr) cytoplasm (Ahr) signal transducer activity (Ahr)
Ahr (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 11 67.60 Quite High
chemokine 9 63.76 Quite High
Neurotransmitter 40 5.00 Very Low Very Low Very Low
anesthesia 9 5.00 Very Low Very Low Very Low
midbrain 8 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 16 78.44 Quite High
Neuroblastoma 72 72.60 Quite High
Eczema 22 72.48 Quite High
Hypersensitivity 2 70.48 Quite High
Drug Induced Neurotoxicity 56 69.44 Quite High
INFLAMMATION 11 67.60 Quite High
Toxicity 18 61.56 Quite High
Sprains And Strains 9 43.20 Quite Low
Syndrome 1 22.28 Low Low
Urticaria 1 21.92 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RT-PCR analysis was performed using mRNA isolated from transfectants to evaluate the expression of AhR mRNA with AhR-specific primers.
Transcription (expression) of AhR
1) Confidence 0.69 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0.20 Pain Relevance 0
In order to confirm the transcriptional activity of the exogenous AhR in N2a-R?
Transcription (activity) of AhR
2) Confidence 0.69 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0 Pain Relevance 0
On the other hand, AhR mRNA was clearly detected (Fig. 2A) in N2a-R?.
Transcription (detected) of AhR
3) Confidence 0.69 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0.16 Pain Relevance 0
AhR mRNA was not detected in either the original Neuro2a cells or N2a-Vc cells transfected with the vector that did not contain the insert.
Neg (not) Transcription (detected) of AhR
4) Confidence 0.69 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0.18 Pain Relevance 0
Transcriptional activation of exogenous AhR
Transcription (Transcriptional) of AhR
5) Confidence 0.66 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0.22 Pain Relevance 0
, we analyzed CYP1A1, GST and AhRR (AhR repressor) mRNA expression as functional markers of AhR [8-11,29].
Spec (analyzed) Transcription (expression) of AhR
6) Confidence 0.66 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0 Pain Relevance 0
In order to confirm the transcriptional activity of the exogenous AhR in N2a-R?
Transcription (activity) of AhR
7) Confidence 0.66 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0 Pain Relevance 0
expressed AhR mRNA at a high level and that N2a-Vc expression of AhR was below the detection limit.
Transcription (expressed) of AhR
8) Confidence 0.66 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0.05 Pain Relevance 0
dose-dependently increased the mRNA levels for aryl hydrocarbon receptor
Transcription (levels) of hydrocarbon receptor
9) Confidence 0.12 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1552025 Disease Relevance 0.51 Pain Relevance 0.07

General Comments

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