INT196003

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Context Info
Confidence 0.30
First Reported 2006
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.38
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cd34) extracellular region (Cd34) cell motility (Cd34)
cell adhesion (Cd34) plasma membrane (Cd34) transcription factor binding (Cd34)
Cd34 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fibrosis 1 99.68 Very High Very High Very High
dexamethasone 40 92.48 High High
Central nervous system 4 59.16 Quite High
cva 4 35.08 Quite Low
Pain 5 31.28 Quite Low
peripheral neuropathy 6 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
aspirin 3 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sarcoma 11 99.78 Very High Very High Very High
Fibrosis 1 99.68 Very High Very High Very High
Hemangiopericytoma 4 97.52 Very High Very High Very High
Gastrointestinal Stromal Tumor 24 96.64 Very High Very High Very High
Cancer 65 94.56 High High
Disease 13 92.80 High High
Metastasis 16 87.88 High High
Malignant Neoplastic Disease 14 84.44 Quite High
Recurrence 7 72.40 Quite High
Lymphangioma 1 69.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The staining for CD34 and VEGFR-3 is most intense out of these [1].
Regulation (intense) of CD34
1) Confidence 0.30 Published 2006 Journal Diagn Pathol Section Body Doc Link PMC1555613 Disease Relevance 0.89 Pain Relevance 0
Even after the detection of the mesenteric primary, the patient was initially treated as a mesenteric sarcoma as histopathology showed a sarcoma which was positive for CD34 and vimentin antigen.
Regulation (positive) of CD34 associated with sarcoma
2) Confidence 0.09 Published 2006 Journal World J Surg Oncol Section Body Doc Link PMC1654154 Disease Relevance 1.52 Pain Relevance 0.11
Hemangiopericytoma is one of the lesions that bears a close resemblance with SFT of soft tissues (fascicular pattern, fibrosis, and vimentin, CD34, and bcl2 immunoreactivity).
Regulation (immunoreactivity) of CD34 associated with fibrosis and hemangiopericytoma
3) Confidence 0.05 Published 2007 Journal Diagn Pathol Section Body Doc Link PMC1913496 Disease Relevance 0.90 Pain Relevance 0.05
A retrospective study addressed specifically this issue; the total number of CD34 cells collected was not affected by previous duration or dose of thalidomide, or duration between thalidomide cessation and mobilization (Ghobrial et al 2003), while in another study the median number of CD34 was affected by the time from thalidomide discontinuation (Abdelkefi et al 2005).
Neg (not) Regulation (affected) of CD34
4) Confidence 0.05 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2374936 Disease Relevance 0.07 Pain Relevance 0.34

General Comments

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