INT196142

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Context Info
Confidence 0.02
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 4.10
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Olfr435) signal transducer activity (Olfr435)
Anatomy Link Frequency
MDA-MB-453 1
Olfr435 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 10 98.48 Very High Very High Very High
Inflammation 18 93.36 High High
agonist 11 59.20 Quite High
metalloproteinase 37 13.96 Low Low
cINOD 4 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Freund adjuvant 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 281 100.00 Very High Very High Very High
Breast Cancer 100 100.00 Very High Very High Very High
Metastasis 73 99.64 Very High Very High Very High
INFLAMMATION 22 93.36 High High
Severe Combined Immunodeficiency 2 91.64 High High
Carcinoma 10 88.52 High High
Immunodeficiency 1 56.40 Quite High
Pathologic Neovascularization 3 55.00 Quite High
Liposarcoma 1 49.20 Quite Low
Reprotox - General 1 2 47.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similar results were reported with VEGF-C overexpressing MDA-MB-435 [30].
Gene_expression (overexpressing) of MDA-MB-435
1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2836381 Disease Relevance 1.03 Pain Relevance 0.08
3-expressing MDA-MB-435 to bone in the experimental metastasis model that bypasses the formation of a primary tumor [39].
Gene_expression (expressing) of MDA-MB-435 associated with cancer and metastasis
2) Confidence 0.01 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1557720 Disease Relevance 2.09 Pain Relevance 0.08
is also expressed in the breast tumor derived cancer cell lines MDA-MB-231, MCF-7, SKBR-3, MDA-MB-435, and MDA-MB-453, irrespective of ER, HER2/neu, or p53 status [13,15,16].
Gene_expression (expressed) of MDA-MB-435 in MDA-MB-453 associated with cancer and breast cancer
3) Confidence 0.01 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2206732 Disease Relevance 0.98 Pain Relevance 0.08

General Comments

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