INT196209

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Context Info
Confidence 0.25
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (REST, SNAP25) endosome (SNAP25) small molecule metabolic process (SNAP25)
intracellular (REST) DNA binding (REST) cytosol (REST)
REST (Homo sapiens)
SNAP25 (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcium channel 11 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 4 5.00 Very Low Very Low Very Low
Repression 3 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 1 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Cerebellar Diseases 1 5.00 Very Low Very Low Very Low
Nervous System Malformation 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low
Ataxia 1 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A number of REST target genes have been found to contain pairs of RE1s arranged in tandem: human SNAP25 and L1CAM recruit REST more effectively than single sites in the same cells (26), while KCNN4 contains a strong, well-conserved RE1 together with a second, more weakly conserved site that is capable of interacting with REST in mouse but not human (42).
REST Binding (recruit) of SNAP25
1) Confidence 0.25 Published 2006 Journal Nucleic Acids Research Section Body Doc Link PMC1557810 Disease Relevance 0 Pain Relevance 0

General Comments

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