INT196321

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Context Info
Confidence 0.17
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.48
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (F2) extracellular space (F2) extracellular region (F2)
Anatomy Link Frequency
lumen 2
F2 (Mus musculus)
Pain Link Frequency Relevance Heat
alcohol 3 80.88 Quite High
fibrosis 14 42.16 Quite Low
peripheral neuropathy 1 11.28 Low Low
Inflammation 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
nud 2 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatic Encephalopathy 46 97.30 Very High Very High Very High
Cirrhosis 69 96.80 Very High Very High Very High
Targeted Disruption 57 93.44 High High
Pancreatic Cancer 33 91.52 High High
Hepatitis 3 79.84 Quite High
Cancer 101 79.44 Quite High
Liver Cancer 3 73.52 Quite High
Metastasis 16 67.60 Quite High
Adenocarcinoma 29 66.32 Quite High
Bacterial Infection 2 55.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Some F2 animals were also crossed together to produce F3 mice.
Negative_regulation (crossed) of Gene_expression (produce) of F2
1) Confidence 0.17 Published 2006 Journal J Carcinog Section Body Doc Link PMC1559682 Disease Relevance 0.72 Pain Relevance 0
The therapeutic benefit of acidifying the gut lumen with synbiotics in cirrhotic patients with minimal HE was demonstrated by Liu et al. [123] who showed that synbiotic/probiotic supplementation ameliorates hepatic function as reflected by reduced bilirubin and albumin levels and prothrombin times [123].
Negative_regulation (reduced) of Gene_expression (levels) of prothrombin in lumen associated with cirrhosis and hepatic encephalopathy
2) Confidence 0.15 Published 2010 Journal Journal of Nutrition and Metabolism Section Body Doc Link PMC3017957 Disease Relevance 0.76 Pain Relevance 0.04

General Comments

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