INT196396

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Context Info
Confidence 0.36
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.09
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Msra) oxidoreductase activity (Msra) aging (Msra)
nucleus (Msra) cytoplasm (Msra)
Msra (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 3 78.44 Quite High
Inflammation 10 5.00 Very Low Very Low Very Low
Spinal cord 6 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 7 100.00 Very High Very High Very High
Targeted Disruption 51 94.80 High High
Stress 109 79.44 Quite High
Lifespan 22 67.52 Quite High
Sprains And Strains 2 60.32 Quite High
Disease 124 58.76 Quite High
Aging 53 58.48 Quite High
Cognitive Disorder 9 50.16 Quite High
Hyperplasia 2 48.48 Quite Low
Cancer 15 42.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, the Ames dwarf mouse not only exhibits enhanced antioxidative defenses, but several of its tissues exhibit increases in heat shock proteins, metallothionein, methionine sulfoxide reductase protein, and glutathione-S-transferase activities, which are known to maintain protein conformation and activity and to counter endogenous and exogenous toxins.
Positive_regulation (increases) of methionine sulfoxide reductase protein associated with shock
1) Confidence 0.36 Published 2006 Journal Age (Dordr) Section Body Doc Link PMC2464727 Disease Relevance 0.64 Pain Relevance 0.04
et al [99] found that the antioxidant enzymes Mn-SOD

(manganesesuperoxide dismutase) and methionine sulfoxide reductase

Positive_regulation (enzymes) of methionine sulfoxide reductase
2) Confidence 0.07 Published 2006 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC1559913 Disease Relevance 0.45 Pain Relevance 0

General Comments

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