INT196430

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Context Info
Confidence 0.14
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.92
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ccnd3) nucleus (Ccnd3) cell cycle (Ccnd3)
cell division (Ccnd3) cytoplasm (Ccnd3)
Anatomy Link Frequency
myoblasts 1
myocytes 1
Ccnd3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 35.04 Quite Low
Eae 3 8.56 Low Low
chemokine 5 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retinoblastoma 2 96.80 Very High Very High Very High
Targeted Disruption 33 90.32 High High
Cancer 60 88.40 High High
Nasopharynx Cancer 53 86.08 High High
Diffuse Large B-cell Lymphoma 56 79.28 Quite High
Stress 8 79.08 Quite High
Metastasis 3 79.04 Quite High
Alzheimer's Dementia 14 77.60 Quite High
Disease 110 73.08 Quite High
Congenital Anomalies 18 72.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ectopic expression of cyclin D3 promoted the formation of the CUGBP1-eIF2 complex in DM1 myotubes and improved fusion of DM1 myoblasts [78].
Gene_expression (expression) of cyclin D3 in myoblasts
1) Confidence 0.14 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.42 Pain Relevance 0
As shown in fig. 4A, all these three oligonucleotides significantly suppressed the expression of c-Myc protein; the reduction in c-Myc expression led to upregulation of p21 expression and downregulation of cyclin D expression.
Gene_expression (expression) of cyclin D
2) Confidence 0.08 Published 2009 Journal J Transl Med Section Body Doc Link PMC2742515 Disease Relevance 0.48 Pain Relevance 0
The group with pattern B demonstrated more frequent expression of Ki-67, cyclin D3, and geminin and showed higher proliferative activity than the group with pattern A.
Gene_expression (expression) of cyclin D3
3) Confidence 0.07 Published 2008 Journal J Hematop Section Body Doc Link PMC2713479 Disease Relevance 0.40 Pain Relevance 0
Confirmation that cyclinD3/cdk4 was implicated in CUG-BP1 translational control came from experiments in which ectopic expression of cyclin D3 corrected the differentiation of DM1 myocytes [91].
Gene_expression (expression) of cyclin D3 in myocytes
4) Confidence 0.07 Published 2008 Journal Current Genomics Section Body Doc Link PMC2694559 Disease Relevance 0 Pain Relevance 0
cyclin D and Cdk4/Cdk6, involved in the G0/G1
Gene_expression (/) of cyclin D
5) Confidence 0.04 Published 2006 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC1559918 Disease Relevance 0.63 Pain Relevance 0

General Comments

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