INT196606

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Context Info
Confidence 0.16
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (CFTR) enzyme binding (CFTR) protein complex (CFTR)
transmembrane transport (CFTR) cytoplasm (CFTR) extracellular space (IFNG)
Anatomy Link Frequency
lung 1
IFNG (Homo sapiens)
CFTR (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 21 81.76 Quite High
Inflammation 34 71.60 Quite High
Inflammatory mediators 20 25.12 Quite Low
substance P 3 8.76 Low Low
bradykinin 10 5.00 Very Low Very Low Very Low
sodium channel 9 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
adenocard 5 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 56 71.60 Quite High
Disease 9 70.56 Quite High
Diarrhoea 8 66.96 Quite High
Volume Depletion And Dehydration 1 60.88 Quite High
Pressure Volume 2 Under Development 2 59.84 Quite High
Hyponatremia 3 58.80 Quite High
Bartter Syndrome 2 57.44 Quite High
Heart Rate Under Development 11 5.00 Very Low Very Low Very Low
Cystic Fibrosis 6 5.00 Very Low Very Low Very Low
Necrosis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IFN gamma has on the other hand been found to activate non CFTR- chloride channel activity by stabilization of mRNA transcripts in human Calu-3 lung epithelial cells with an associated increase in short-circuit current in the Ussing chamber [51].
IFN gamma Positive_regulation (activate) of CFTR in lung
1) Confidence 0.16 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1562419 Disease Relevance 0.45 Pain Relevance 0.16

General Comments

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