INT196612

Context Info Confidence 0.01 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.19 Pain Relevance 0.29

extracellular space (KNG1) extracellular region (KNG1) plasma membrane (KNG1)

Anatomy Link Frequency proximal 2 KNG1 (Homo sapiens) NA (Homo sapiens)

Pain Link Frequency Relevance Heat bradykinin 10 100.00 cytokine 21 72.60 Inflammation 34 55.12 Kinase C 2 46.76 sodium channel 9 38.48 Inflammatory mediators 20 5.00 fibrosis 6 5.00 adenocard 5 5.00 agonist 5 5.00 substance P 3 5.00

Disease Link Frequency Relevance Heat Natriuresis 2 78.96 INFLAMMATION 56 55.12 Renal Disease 1 54.08 Pyelonephritis 4 45.84 Pressure And Volume Under Development 4 15.00 Heart Rate Under Development 11 5.00 Disease 9 5.00 Diarrhoea 8 5.00 Cystic Fibrosis 6 5.00 Necrosis 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Bradykinin revealed dichotomous effects in another study where it was found to increase Na/K ATPase activity through interaction with B1 bradykinin receptors but inhibited Na/K ATPase function by interaction with the B2 bradykinin receptors on renal proximal tubular cells in vitro [109].

bradykinin Binding (interaction) of in proximal Negative_regulation (inhibited) of Na associated with bradykinin

1) Confidence 0.01 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1562419 Disease Relevance 0.19 Pain Relevance 0.29

General Comments

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