INT196630

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNF) extracellular space (TNF) extracellular region (TNF)
plasma membrane (TNF) intracellular (TNF) extracellular matrix organization (TNF)
Anatomy Link Frequency
colon 2
TNF (Homo sapiens)
NA (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 21 94.92 High High
Inflammation 34 50.00 Quite Low
Inflammatory mediators 20 6.16 Low Low
bradykinin 10 5.00 Very Low Very Low Very Low
sodium channel 9 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
adenocard 5 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colitis 3 78.80 Quite High
Inflammatory Bowel Disease 4 77.60 Quite High
INFLAMMATION 56 50.00 Quite Low
Heart Rate Under Development 11 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Diarrhoea 8 5.00 Very Low Very Low Very Low
Cystic Fibrosis 6 5.00 Very Low Very Low Very Low
Necrosis 5 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Pyelonephritis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TNF was found to have the opposite effect on Na K 2Cl symporter expression in rat colon where it reduced both Na/K ATPase and Na K 2Cl symporter expression and activity in surface and crypt colonocytes [88].
TNF Regulation (effect) of Gene_expression (expression) of Na in colon
1) Confidence 0.04 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1562419 Disease Relevance 0.16 Pain Relevance 0.08

General Comments

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