INT196672

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Context Info
Confidence 0.41
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (CFTR) ATPase activity (CFTR) plasma membrane (CFTR)
enzyme binding (CFTR) protein complex (CFTR) transmembrane transport (CFTR)
CFTR (Homo sapiens)
Pain Link Frequency Relevance Heat
sodium channel 18 98.78 Very High Very High Very High
Inflammation 68 50.00 Quite Low
Inflammatory mediators 40 33.72 Quite Low
potassium channel 4 32.32 Quite Low
cytokine 42 5.00 Very Low Very Low Very Low
bradykinin 20 5.00 Very Low Very Low Very Low
fibrosis 12 5.00 Very Low Very Low Very Low
adenocard 10 5.00 Very Low Very Low Very Low
agonist 10 5.00 Very Low Very Low Very Low
substance P 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 112 50.00 Quite Low
Ear Disease 2 23.36 Low Low
Heart Rate Under Development 22 5.00 Very Low Very Low Very Low
Disease 18 5.00 Very Low Very Low Very Low
Diarrhoea 16 5.00 Very Low Very Low Very Low
Cystic Fibrosis 12 5.00 Very Low Very Low Very Low
Necrosis 10 5.00 Very Low Very Low Very Low
Cancer 10 5.00 Very Low Very Low Very Low
Pyelonephritis 8 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Amiloride is used to block sodium channels and forskolin, a stimulator of the adenylate cyclase, which activates CFTR mediated chloride secretion through increase in intracellular cAMP, is used to test CFTR function.


Positive_regulation (activates) of Localization (secretion) of CFTR associated with sodium channel
1) Confidence 0.41 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1562419 Disease Relevance 0 Pain Relevance 0.05
Amiloride is used to block sodium channels and forskolin, a stimulator of the adenylate cyclase, which activates CFTR mediated chloride secretion through increase in intracellular cAMP, is used to test CFTR function.


Positive_regulation (mediated) of Localization (secretion) of CFTR associated with sodium channel
2) Confidence 0.27 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1562419 Disease Relevance 0 Pain Relevance 0.05

General Comments

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