INT196691

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Context Info
Confidence 0.10
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.23
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ATPase activity (DNAH8) cytoskeleton (DNAH8) cilium (DNAH8)
cytoplasm (DNAH8)
DNAH8 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 6 99.90 Very High Very High Very High
Inflammation 34 78.48 Quite High
cytokine 21 77.44 Quite High
Inflammatory response 3 10.96 Low Low
Inflammatory mediators 20 5.00 Very Low Very Low Very Low
bradykinin 10 5.00 Very Low Very Low Very Low
sodium channel 9 5.00 Very Low Very Low Very Low
adenocard 5 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cystic Fibrosis 6 99.90 Very High Very High Very High
Sepsis 4 91.84 High High
Heart Rate Under Development 11 90.08 High High
Syndrome 59 88.64 High High
INFLAMMATION 56 78.48 Quite High
Cancer 5 76.24 Quite High
Necrosis 5 75.76 Quite High
Contracture 20 63.72 Quite High
Bacterial Pneumonia 1 45.44 Quite Low
Meningitis 3 38.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This mutation maps to a domain of the protein that is not involved in direct interactions with other troponins, but it causes increased ATPase activity and Ca2+-dependent force generation [11].
Positive_regulation (causes) of Positive_regulation (increased) of ATPase
1) Confidence 0.10 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2663550 Disease Relevance 0.23 Pain Relevance 0
In isolated congenital CFTR dysfunction (cystic fibrosis) an increase in sodium transport by an increase in apical ENaC and basolateral Na/K ATPase activity in the airways can compensate for a reduction in alveolar chloride and sodium transport.
Positive_regulation (increase) of Positive_regulation (increase) of ATPase associated with fibrosis and cystic fibrosis
2) Confidence 0.04 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1562419 Disease Relevance 1.00 Pain Relevance 0.13

General Comments

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