INT196826

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Context Info
Confidence 0.10
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ppp1r1b, Ppp1cc) nucleus (Ppp1r1b, Ppp1cc) mitochondrion (Ppp1cc)
intracellular (Ppp1r1b) carbohydrate metabolic process (Ppp1cc) protein complex (Ppp1cc)
Anatomy Link Frequency
striatum 1
Ppp1r1b (Mus musculus)
Ppp1cc (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 119 99.92 Very High Very High Very High
Glutamate 31 76.00 Quite High
Neurotransmitter 3 64.48 Quite High
adenocard 1 60.64 Quite High
long-term potentiation 8 59.64 Quite High
Opioid 1 58.80 Quite High
projection neuron 4 5.00 Very Low Very Low Very Low
Action potential 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
nMDA receptor 2 5.00 Very Low Very Low Very Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the medium spiny neurons of the striatum, the balance between PKA and PP1 is heavily regulated by the phosphoprotein DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) [13].
DARPP-32 Regulation (regulated) of PP1 in striatum associated with dopamine
1) Confidence 0.10 Published 2006 Journal PLoS Computational Biology Section Body Doc Link PMC1562452 Disease Relevance 0 Pain Relevance 0.51

General Comments

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