INT196928

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (E2f2) cell cycle (E2f2) DNA binding (E2f2)
transcription factor binding (E2f2)
Anatomy Link Frequency
glands 2
E2f2 (Mus musculus)
Pain Link Frequency Relevance Heat
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenoma 4 98.56 Very High Very High Very High
Pituitary Cancer 27 92.04 High High
Targeted Disruption 11 86.60 High High
Cancer 3 52.32 Quite High
Prolactinoma 3 5.00 Very Low Very Low Very Low
Retinoblastoma 2 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low
Hypopituitarism 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, by RT-PCR and ChIPs on tissues, expression of E2F-target genes, such as CDC1 and TK1, was shown to be enhanced, and E2F1 to be more acetylated in adenomas compared to normal glands (unpublished data).
Positive_regulation (enhanced) of Gene_expression (expression) of E2F in glands associated with adenoma
1) Confidence 0.01 Published 2006 Journal Cell Div Section Body Doc Link PMC1563461 Disease Relevance 0.92 Pain Relevance 0

General Comments

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