INT196942

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Context Info
Confidence 0.39
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (E2f1, Hmga2) nucleus (E2f1, Hmga2) cell cycle (E2f1, Hmga2)
transcription factor binding (E2f1, Hmga2) nuclear chromosome (Hmga2) mitochondrion (E2f1)
E2f1 (Mus musculus)
Hmga2 (Mus musculus)
Pain Link Frequency Relevance Heat
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pituitary Cancer 27 99.20 Very High Very High Very High
Cancer 3 78.64 Quite High
Targeted Disruption 11 76.08 Quite High
Adenoma 4 72.92 Quite High
Prolactinoma 3 5.00 Very Low Very Low Very Low
Retinoblastoma 2 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low
Hypopituitarism 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, even though HMGA2 is still able to bind pRB in the absence of E2F1, there are no other proteins belonging to the E2F family, whose DNA binding activity is enhanced following the HMGA2/pRB interaction.
E2F1 Binding (bind) of HMGA2
1) Confidence 0.39 Published 2006 Journal Cell Div Section Body Doc Link PMC1563461 Disease Relevance 0.87 Pain Relevance 0

General Comments

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