INT196950

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Rb1, E2f2) cell cycle (Rb1, E2f2) DNA binding (Rb1, E2f2)
transcription factor binding (Rb1, E2f2) enzyme binding (Rb1) cell division (Rb1)
Rb1 (Mus musculus)
E2f2 (Mus musculus)
Pain Link Frequency Relevance Heat
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pituitary Cancer 27 96.56 Very High Very High Very High
Retinoblastoma 2 78.96 Quite High
Prolactinoma 3 66.76 Quite High
Targeted Disruption 11 63.68 Quite High
Benign Tumor 1 59.84 Quite High
Repression 2 48.24 Quite Low
Malignant Neoplastic Disease 1 45.76 Quite Low
Adenoma 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
pRB controls cell cycle progression through its interaction with the E2F family of transcription factors [26,27], whose activity is crucial for the expression of several genes required to enter the S phase of the cell cycle [28,29].
pRB Binding (interaction) of E2F
1) Confidence 0.01 Published 2006 Journal Cell Div Section Body Doc Link PMC1563461 Disease Relevance 0.60 Pain Relevance 0

General Comments

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