INT196954

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Context Info
Confidence 0.40
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (E2f1) endoplasmic reticulum (Atp8a1) nucleus (E2f1)
cell cycle (E2f1) DNA binding (E2f1) transcription factor binding (E2f1)
Atp8a1 (Mus musculus)
E2f1 (Mus musculus)
Pain Link Frequency Relevance Heat
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 2 98.98 Very High Very High Very High
Retinoblastoma 2 66.40 Quite High
Pituitary Cancer 27 62.52 Quite High
Cancer 3 51.20 Quite High
Prolactinoma 3 32.72 Quite Low
Targeted Disruption 11 29.64 Quite Low
Benign Tumor 1 25.80 Quite Low
Malignant Neoplastic Disease 1 11.72 Low Low
Adenoma 4 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is an active repression that pRB exerts on E2F1-mediated transcription by recruiting class I histone deacetylase proteins (HDAC1) to the E2F1-sites.
class I Binding (recruiting) of E2F1 associated with repression
1) Confidence 0.40 Published 2006 Journal Cell Div Section Body Doc Link PMC1563461 Disease Relevance 0.49 Pain Relevance 0

General Comments

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