INT197101

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Context Info
Confidence 0.38
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (FLT4) plasma membrane (FLT4) nucleus (FLT4)
cytoplasm (FLT4)
Anatomy Link Frequency
keratinocytes 2
FLT4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 13 67.60 Quite High
Paracetamol 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 98.44 Very High Very High Very High
Lymphedema 77 92.64 High High
Cancer 7 64.48 Quite High
Necrosis 1 64.00 Quite High
Disease 18 52.16 Quite High
Lymphatic Filariasis 23 44.80 Quite Low
Intestinal Volvulus 3 39.20 Quite Low
Helminth Infection 60 38.88 Quite Low
Keratitis 1 35.48 Quite Low
Infection 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this genetic model, sVEGFR-3 is secreted at high levels by basal epidermal keratinocytes and binds the lymphangiogenesis factors VEGF-C and VEGF-D, thereby preventing them from activating membrane-bound VEGFR-3 on lymphatic endothelium [36].
Positive_regulation (levels) of Localization (secreted) of sVEGFR-3 in keratinocytes
1) Confidence 0.38 Published 2006 Journal PLoS Pathogens Section Body Doc Link PMC1564427 Disease Relevance 0.77 Pain Relevance 0.06

General Comments

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