INT197157

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Context Info
Confidence 0.51
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 19
Total Number 20
Disease Relevance 11.33
Pain Relevance 0.40

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peptidase activity (CAPN7) nucleus (CAPN7) intracellular (CAPN7)
Anatomy Link Frequency
spores 1
ureter 1
kidney 1
CAPN7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 17 95.48 Very High Very High Very High
cva 8 91.36 High High
Pain 20 54.08 Quite High
lumbar region 10 52.72 Quite High
Inflammation 4 6.00 Low Low
corticosteroid 5 5.00 Very Low Very Low Very Low
abdominal pain 5 5.00 Very Low Very Low Very Low
Dysuria 5 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
vincristine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aspergillus Infection 244 100.00 Very High Very High Very High
Infection 190 99.92 Very High Very High Very High
Diabetes Mellitus 90 99.84 Very High Very High Very High
Stress Incontinence 35 98.96 Very High Very High Very High
Fungal Infection 119 98.60 Very High Very High Very High
Urinary Tract Infection 15 98.14 Very High Very High Very High
Invasive Pulmonary Aspergillosis 550 97.60 Very High Very High Very High
Angina 17 95.48 Very High Very High Very High
Fever 32 93.64 High High
Mediastinitis 32 93.36 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our case, no history of urinary tract infection and passage of fungal masses per urethra prior to ICPL and instrumentation suggest that the Aspergillus was introduced into the urinary tract during ureteroscopy and placement of stent in the ureter.
Gene_expression (introduced) of Aspergillus in ureter associated with stress incontinence and urinary tract infection
1) Confidence 0.51 Published 2007 Journal BMC Infect Dis Section Body Doc Link PMC1906785 Disease Relevance 1.06 Pain Relevance 0
Quantitative PCR has several advantages when used for the detection of Aspergillus spp.
Gene_expression (detection) of Aspergillus spp
2) Confidence 0.49 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.76 Pain Relevance 0
Thus the clinical ramifications of incorrectly calling a Paecilomyces infection an Aspergillus infection are likely to be small.
Gene_expression (infection) of Aspergillus associated with aspergillus infection and infection
3) Confidence 0.49 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.38 Pain Relevance 0
It is also noteworthy to mention that the IAC qPCR multiplexed with the Aspergillus qPCR assay did not manifest any inhibition even in the presence of human genomic DNA as high as 1.5 ?
Gene_expression (assay) of Aspergillus
4) Confidence 0.49 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.12 Pain Relevance 0
For all BALs with any Aspergillus DNA detected by qPCR, the median quantity of Aspergillus DNA was 173 fg with a range of 4 fg to > 1500 pg per pellet.
Gene_expression (detected) of Aspergillus
5) Confidence 0.49 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.40 Pain Relevance 0
We verified the ability of our Aspergillus qPCR assay to successfully amplify 10 fg of A. fumigatus genomic DNA (< 1 Aspergillus genome) in the presence of 1 ?
Gene_expression (genome) of Aspergillus
6) Confidence 0.49 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0 Pain Relevance 0
Very few studies related to fungal PCR diagnostics analyzing BAL fluid have incorporated an IAC [33,34], only one of which focused on Aspergillus detection in BAL.
Gene_expression (detection) of Aspergillus
7) Confidence 0.49 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.17 Pain Relevance 0
Extensive analytical specificity testing showed that among the 23 non-Aspergillus fungal species, our Aspergillus qPCR assay had significant cross-reactivity only with Penicillium chrysogenum and Paecilomyces variotii.
Gene_expression (assay) of Aspergillus
8) Confidence 0.49 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.26 Pain Relevance 0
We verified the ability of our Aspergillus qPCR assay to successfully amplify 10 fg of A. fumigatus genomic DNA (< 1 Aspergillus genome) in the presence of 1 ?
Gene_expression (assay) of Aspergillus
9) Confidence 0.49 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0 Pain Relevance 0
For this episode, the Aspergillus qPCR was convincingly positive with 2 pg of Aspergillus DNA found in the pellet.
Gene_expression (positive) of Aspergillus
10) Confidence 0.49 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.55 Pain Relevance 0
For this episode, the Aspergillus qPCR was convincingly positive with 2 pg of Aspergillus DNA found in the pellet.
Gene_expression (positive) of Aspergillus
11) Confidence 0.49 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.55 Pain Relevance 0
Diagnostic utility of the Aspergillus qPCR, culture and histology
Gene_expression (utility) of Aspergillus
12) Confidence 0.49 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2440748 Disease Relevance 0.34 Pain Relevance 0
The identification of the source of Aspergillus spp. is often difficult, and there are no guidelines for the administration of pre-emptive therapy in this population.
Gene_expression (source) of Aspergillus
13) Confidence 0.48 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2955057 Disease Relevance 0.44 Pain Relevance 0
We focus on the clinical dilemmas that could be met and cover the early diagnosis, the difficulties associated with detection of the source of Aspergillus spp. and the management of our patient.


Gene_expression (source) of Aspergillus
14) Confidence 0.48 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2955057 Disease Relevance 1.18 Pain Relevance 0.11
Analysis of a large series of patients revealed that Aspergillus infection of the kidney constitutes about 30% (27/90) of total renal fungal infection and majority (63%) results from disseminated infection [10].
Gene_expression (infection) of Aspergillus in kidney associated with fungal infection, aspergillus infection and infection
15) Confidence 0.44 Published 2007 Journal BMC Infect Dis Section Body Doc Link PMC1906785 Disease Relevance 1.14 Pain Relevance 0
Renal Aspergillus infection usually results from disseminated fungal infection having underlying immunocompromised states.
Gene_expression (infection) of Aspergillus associated with fungal infection and aspergillus infection
16) Confidence 0.44 Published 2007 Journal BMC Infect Dis Section Body Doc Link PMC1906785 Disease Relevance 1.26 Pain Relevance 0
So far, there is no report of Aspergillus infection of urinary tract following ICPL.
Gene_expression (infection) of Aspergillus associated with aspergillus infection
17) Confidence 0.44 Published 2007 Journal BMC Infect Dis Section Body Doc Link PMC1906785 Disease Relevance 0.91 Pain Relevance 0
Diagnosis of localized primary renal Aspergillus infection in diabetic patients requires careful investigations due to its benign presentation and lack of associated systemic clinical features.
Gene_expression (infection) of Aspergillus associated with diabetes mellitus and aspergillus infection
18) Confidence 0.44 Published 2007 Journal BMC Infect Dis Section Abstract Doc Link PMC1906785 Disease Relevance 1.03 Pain Relevance 0.08
We were unable to confidently differentiate the Aspergillus spores from Penicillium spores because of their morphologic similarity.
Gene_expression (spores) of Aspergillus in spores
19) Confidence 0.03 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1570051 Disease Relevance 0 Pain Relevance 0
The Aspergillus galactomannan antigen was negative.
Neg (negative) Gene_expression (negative) of Aspergillus
20) Confidence 0.02 Published 2007 Journal BMC Infect Dis Section Body Doc Link PMC1878481 Disease Relevance 0.79 Pain Relevance 0.21

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