INT19716

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Context Info
Confidence 0.41
First Reported 1990
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 2.18
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Ecd) nucleus (Ecd) cellular_component (Ecd)
cytoplasm (Ecd)
Anatomy Link Frequency
sensory neurons 1
Ecd (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 12 99.00 Very High Very High Very High
imagery 27 96.44 Very High Very High Very High
Morphine 1 96.12 Very High Very High Very High
dexamethasone 1 83.76 Quite High
Hippocampus 10 72.72 Quite High
cerebral cortex 1 65.52 Quite High
Inflammation 6 65.36 Quite High
fibrosis 1 65.20 Quite High
Thalamus 1 63.20 Quite High
medulla 1 60.00 Quite High
Disease Link Frequency Relevance Heat
Pathologic Constriction 8 99.96 Very High Very High Very High
Cv General 4 Under Development 55 99.00 Very High Very High Very High
Diabetes Mellitus 7 96.24 Very High Very High Very High
Cataract 43 95.24 Very High Very High Very High
Glaucoma 9 91.56 High High
Open-angle Glaucoma 1 81.72 Quite High
Amaurosis Fugax 2 81.52 Quite High
Stroke 34 80.52 Quite High
Myopia 23 79.36 Quite High
Ocular Hypertension 17 76.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Purified TrkB ECD or ICD proteins (10 µg/each) were incubated with different [3H-deoxygedunin] in 1 ml binding buffer (0.05 M Na/K phosphate buffer (pH 7.1), 200 mM NaCl) (1 nM [3H]deoxygedunin ?
Gene_expression (Purified) of ECD
1) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2903477 Disease Relevance 0 Pain Relevance 0.04
Purified TrkB ECD or ICD proteins (10 µg/each) were incubated with different [3H-deoxygedunin] in 1 ml binding buffer (0.05 M Na/K phosphate buffer (pH 7.1), 200 mM NaCl) (1 nM [3H]deoxygedunin ?
Gene_expression (proteins) of ECD
2) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2903477 Disease Relevance 0 Pain Relevance 0.04
Change in ECD was expressed as a percentage, obtained by dividing the difference between postoperative and preoperative values by the preoperative value.
Gene_expression (expressed) of ECD
3) Confidence 0.15 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC3009998 Disease Relevance 0 Pain Relevance 0.04
m axonal length; and Akt inh. + B4-ECD, 8.48 ± 1.58 clusters/100-?
Gene_expression (inh.) of B4-ECD
4) Confidence 0.11 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2364689 Disease Relevance 0 Pain Relevance 0
m axonal length; and Akt inh. + B4-ECD, 8.48 ± 1.58 clusters/100-?
Gene_expression (length) of B4-ECD
5) Confidence 0.11 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2364689 Disease Relevance 0 Pain Relevance 0
To verify that the increase in surface clusters we detected in response to B4-ECD treatment was mediated by Type III Nrg1 acting as a receptor, we assessed the response of sensory neurons treated with B4-ECD in the presence of 2 ?
Gene_expression (with) of B4-ECD in sensory neurons
6) Confidence 0.11 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2364689 Disease Relevance 0 Pain Relevance 0
The drop in ECD was less in the CLE than in the ICL group (4.47% versus 5.67%, respectively).
Gene_expression (less) of ECD
7) Confidence 0.11 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2874272 Disease Relevance 0.99 Pain Relevance 0.07
Administration of 3-methylcholanthrene, selectively induced the levels of ethoxycoumarin O-deethylase (ECD) and arylhydrocarbon hydroxylase, although the levels of total P-450 were not increased. 3-Methylcholanthrene induction was also accompanied by a shift in the absorption maximum of the reduced carbon monoxide difference spectrum from 452 to 448 nm.
Gene_expression (levels) of ECD
8) Confidence 0.09 Published 1990 Journal Brain Res. Section Abstract Doc Link 2085761 Disease Relevance 0 Pain Relevance 0.22
ECD detected stenoses ?
Gene_expression (detected) of ECD associated with pathologic constriction
9) Confidence 0.05 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2906428 Disease Relevance 1.19 Pain Relevance 0.17

General Comments

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