INT197225

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Context Info
Confidence 0.35
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 2.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Kars) translation (Kars) ligase activity (Kars)
cytoplasm (Kars)
Anatomy Link Frequency
amygdala 3
neurons 2
spinal cord 1
Kars (Mus musculus)
Pain Link Frequency Relevance Heat
substantia gelatinosa 171 99.64 Very High Very High Very High
Hippocampus 6 98.72 Very High Very High Very High
GABAergic 39 98.08 Very High Very High Very High
amygdala 3 97.72 Very High Very High Very High
Spinal cord 54 97.20 Very High Very High Very High
gABA 36 86.08 High High
Dorsal horn 33 83.64 Quite High
antagonist 24 75.44 Quite High
Dorsal horn neuron 15 73.64 Quite High
Calcium channel 3 69.92 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 12 25.44 Quite Low
Epilepsy 3 7.36 Low Low
Anxiety Disorder 3 6.56 Low Low
Pain 9 5.28 Low Low
Nociception 21 5.00 Very Low Very Low Very Low
Overdose 3 5.00 Very Low Very Low Very Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low
Inflammatory Pain 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tonic activation of GluR5 KARs modulate inhibitory synaptic transmission in SG neurons
Regulation (modulate) of Positive_regulation (activation) of KARs in neurons associated with substantia gelatinosa
1) Confidence 0.35 Published 2006 Journal Mol Pain Section Body Doc Link PMC1570342 Disease Relevance 0 Pain Relevance 0.81
Previous studies have shown that endogenous activation of presynaptic GluR5 KARs in interneurons modulate the inhibitory transmission in hippocampus, basolateral amygdala and spinal cord [25,41,44].
Regulation (modulate) of Positive_regulation (activation) of KARs in amygdala associated with hippocampus, amygdala and spinal cord
2) Confidence 0.35 Published 2006 Journal Mol Pain Section Body Doc Link PMC1570342 Disease Relevance 0 Pain Relevance 0.87
Previous studies have shown that endogenous activation of presynaptic GluR5 KARs in interneurons modulate the inhibitory transmission in hippocampus, basolateral amygdala and spinal cord [25,41,44].
Regulation (modulate) of in spinal cord Positive_regulation (activation) of KARs in amygdala associated with hippocampus, amygdala and spinal cord
3) Confidence 0.12 Published 2006 Journal Mol Pain Section Body Doc Link PMC1570342 Disease Relevance 0 Pain Relevance 0.87

General Comments

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