INT197226

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Rora) DNA binding (Rora)
Anatomy Link Frequency
neurons 2
Rora (Mus musculus)
Pain Link Frequency Relevance Heat
substantia gelatinosa 57 100.00 Very High Very High Very High
antagonist 8 100.00 Very High Very High Very High
Glutamate 3 99.64 Very High Very High Very High
Dorsal horn 11 93.56 High High
GABAergic 13 79.52 Quite High
Spinal cord 18 66.96 Quite High
gABA 12 64.96 Quite High
nMDA receptor 3 61.08 Quite High
agonist 4 57.04 Quite High
Dorsal horn neuron 5 50.40 Quite High
Disease Link Frequency Relevance Heat
Nociception 7 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Inflammatory Pain 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To investigate whether presynaptic GluR5 KARs are activated by endogenous glutamate, we examined the effect of bath application of GluR5 antagonist, LY293558, on sIPSCs in spinal SG neurons.
Spec (examined) Regulation (effect) of Gene_expression (neurons) of SG in neurons associated with substantia gelatinosa, glutamate and antagonist
1) Confidence 0.04 Published 2006 Journal Mol Pain Section Body Doc Link PMC1570342 Disease Relevance 0 Pain Relevance 0.71

General Comments

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