INT197231

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Context Info
Confidence 0.19
First Reported 2006
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.13
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grik1, Gabrg1) plasma membrane (Grik1, Gabrg1)
Anatomy Link Frequency
spinal 1
Grik1 (Mus musculus)
Gabrg1 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 47 100.00 Very High Very High Very High
amygdala 121 99.36 Very High Very High Very High
Dorsal horn neuron 5 99.28 Very High Very High Very High
Pyramidal cell 25 94.20 High High
agonist 8 94.12 High High
substantia gelatinosa 57 89.52 High High
spinal dorsal horn 6 84.04 Quite High
Hippocampus 4 82.12 Quite High
superficial lamina 1 77.36 Quite High
GABAergic 30 76.28 Quite High
Disease Link Frequency Relevance Heat
Nociception 7 71.28 Quite High
Targeted Disruption 10 56.20 Quite High
Anxiety Disorder 51 50.00 Quite Low
Pain 4 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 2 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Ganglion Cysts 1 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Bidirectional modulation of GABA release by presynaptic GluR5 (measured by both mIPSCs and eIPSCs) was reported in the young rat BLA, in which different types of GluR5-containing KA receptors, with different agonist affinities, were proposed to mediate the biphasic effect [25].
GluR5 Regulation (modulation) of GABA release associated with gaba, agonist and amygdala
1) Confidence 0.19 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1766473 Disease Relevance 0 Pain Relevance 0.58
Thus, both GluR5 and GluR6 may regulate presynaptic GABA and glycine release in cultured spinal dorsal horn neurons.
GluR5 Spec (may) Regulation (regulate) of GABA in spinal associated with gaba and dorsal horn neuron
2) Confidence 0.17 Published 2006 Journal Mol Pain Section Body Doc Link PMC1570342 Disease Relevance 0.13 Pain Relevance 0.64

General Comments

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