INT197284

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Context Info
Confidence 0.13
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 1.35
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Olfr153) signal transducer activity (Olfr153)
Olfr153 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 6 95.92 Very High Very High Very High
TRP channel 24 35.16 Quite Low
Neurotransmitter 20 5.00 Very Low Very Low Very Low
Inflammation 7 5.00 Very Low Very Low Very Low
Mechanosensation 6 5.00 Very Low Very Low Very Low
midbrain 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
tail-flick 3 5.00 Very Low Very Low Very Low
qutenza 3 5.00 Very Low Very Low Very Low
Thermal hyperalgesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroblastoma 36 99.50 Very High Very High Very High
Cytomegalovirus Infection 8 99.32 Very High Very High Very High
Drug Induced Neurotoxicity 28 95.84 Very High Very High Very High
Immunization 2 81.40 Quite High
Polycystic Kidney Disease 21 60.52 Quite High
Stress 9 52.16 Quite High
Renal Failure 3 48.16 Quite Low
Neurodegenerative Disease 8 30.12 Quite Low
Myelodysplastic Syndromes 3 6.36 Low Low
Viral Meningitis 38 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The murine neuroblastoma cell line, Neuro2a, was transfected with AhR cDNA in the expression vector (pcDNA4/V5-His), which includes the V5 epitope and the cytomegalovirus promoter.
Gene_expression (expression) of V5 associated with neuroblastoma and cytomegalovirus infection
1) Confidence 0.13 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0.29 Pain Relevance 0
Similarly, a V5 tag was engineered into the second extracellular loop of human TRPP2 (TRPP2-V5 loop; in the cdm8 vector).
Gene_expression (loop) of V5
2) Confidence 0.12 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2500130 Disease Relevance 0.11 Pain Relevance 0.05
The murine neuroblastoma cell line, Neuro2a, was transfected with AhR cDNA in the expression vector (pcDNA4/V5-His), which includes the V5 epitope and the cytomegalovirus promoter.
Gene_expression (transfected) of V5 associated with neuroblastoma and cytomegalovirus infection
3) Confidence 0.11 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0.29 Pain Relevance 0
The murine neuroblastoma cell line, Neuro2a, was transfected with AhR cDNA in the expression vector (pcDNA4/V5-His), which includes the V5 epitope and the cytomegalovirus promoter.
Gene_expression (expression) of V5 associated with neuroblastoma and cytomegalovirus infection
4) Confidence 0.11 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0.29 Pain Relevance 0
In contrast to the TRPV4-V5 loop protein, expression of which stimulated efficient conversion of the AP substrate, the enzymatic reaction on cells expressing TRPP2-V5 loop protein resulted in a modest increase in the amount of AP product as compared with the mock-transfected cells (21% increase on average).
Gene_expression (expression) of V5
5) Confidence 0.11 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2500130 Disease Relevance 0 Pain Relevance 0
After digestion with HindIII and XhoI, the PCR product was cloned into the mammalian expression vector pcDNA4/V5-His (Invitrogen Japan KK, Tokyo, Japan) digested with HindIII and XhoI.
Gene_expression (expression) of V5
6) Confidence 0.10 Published 2006 Journal Environ Health Section Body Doc Link PMC1570454 Disease Relevance 0.28 Pain Relevance 0
The efficacy of TPRV4 siRNA sequences was tested by coexpressing different siRNA-expressing pSuper plasmids with cTRPV4.V5 in HEK 293T cells and testing the amount of cTRPV4.V5 protein by Western blotting.
Gene_expression (coexpressing) of V5
7) Confidence 0.10 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2500130 Disease Relevance 0 Pain Relevance 0.03
All 100 V0 sera and the three PRNT50 negative sera of V5 were detected as negative by the IgG IIFT.
Neg (negative) Gene_expression (negative) of V5
8) Confidence 0.03 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2982812 Disease Relevance 0.08 Pain Relevance 0

General Comments

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