INT197379

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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 1.87
Pain Relevance 2.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neurons 1
cortex 1
Tbs1 (Mus musculus)
Ltp (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 296 100.00 Very High Very High Very High
Hippocampus 44 99.16 Very High Very High Very High
depression 23 93.68 High High
nMDA receptor 32 93.52 High High
antagonist 8 92.80 High High
Action potential 7 68.56 Quite High
amygdala 3 58.16 Quite High
Anterior cingulate cortex 34 43.60 Quite Low
imagery 10 30.52 Quite Low
Glutamate 7 8.44 Low Low
Disease Link Frequency Relevance Heat
Depression 23 93.68 High High
Targeted Disruption 132 92.96 High High
Sprains And Strains 20 88.80 High High
Li-fraumeni Syndrome 12 86.88 High High
Anaerobic Bacterial Infections 13 69.44 Quite High
Convulsion 70 59.00 Quite High
Autism 6 50.00 Quite Low
Syndrome 30 5.00 Very Low Very Low Very Low
Epilepsy 18 5.00 Very Low Very Low Very Low
Shock 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that TBS induced significant LTP in the cingulate neurons (151.8 ± 12.7%; n = 8, P < 0.05 compared with baseline response) (Fig. 3B).
TBS Positive_regulation (induced) of LTP in neurons associated with long-term potentiation
1) Confidence 0.07 Published 2007 Journal Mol Pain Section Body Doc Link PMC2245920 Disease Relevance 0 Pain Relevance 0.54
Confirming the results obtained with 8 × 8 3D MEAs (Fig. 3B, 4A), TBS induced notable LTP in recordings performed by 5 × 13 3D MEAs (Fig. 7A; 129S5: 182 ± 38 %; t(14) = -8.33; P < 0.001 and C57: 173 ± 16%; t(6) = -13.35; P < 0.001).
TBS Positive_regulation (induced) of LTP associated with long-term potentiation
2) Confidence 0.06 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1574331 Disease Relevance 0.30 Pain Relevance 0.31
We examined LTP induced by either high frequency stimulation or TBS.
TBS Spec (examined) Positive_regulation (induced) of LTP associated with long-term potentiation
3) Confidence 0.03 Published 2010 Journal Mol Autism Section Body Doc Link PMC3019144 Disease Relevance 0 Pain Relevance 0.18
LTP was induced by either a high-frequency stimulus (four trains of 100-Hz, 1-s stimulations separated by 5 min) or TBS (15 bursts of four pulses at 100 Hz separated by 200 ms).
TBS Positive_regulation (induced) of LTP associated with long-term potentiation
4) Confidence 0.02 Published 2010 Journal Mol Autism Section Body Doc Link PMC3019144 Disease Relevance 0.43 Pain Relevance 0.22
The TBS that induces LTP causes bidirectional trafficking of EP2 and EP3 into the membrane and the cytosol, respectively, which results in an increase in EP2 and a decrease in EP3 at the membrane.
TBS Positive_regulation (induces) of LTP associated with long-term potentiation
5) Confidence 0.02 Published 2007 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2759147 Disease Relevance 0 Pain Relevance 0.43
To determine if this enhancement was due to increased responsiveness during the theta burst stimulation (TBS) used to induce LTP we examined the fEPSPs during TBS.
TBS Positive_regulation (induce) of LTP
6) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695674 Disease Relevance 1.14 Pain Relevance 0.16
Our previous work has shown that BDNF increases the efficacy of synaptic transmission and TBS-induced LTP in the visual cortex (Akaneya et al. 1997).
TBS Positive_regulation (induced) of LTP in cortex associated with long-term potentiation
7) Confidence 0.01 Published 2007 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2759147 Disease Relevance 0 Pain Relevance 0.36

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