INT197444

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Context Info
Confidence 0.27
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.50
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Aldh1a3) cytoplasm (Aldh1a3)
Anatomy Link Frequency
synapses 1
cortex 1
Aldh1a3 (Mus musculus)
Pain Link Frequency Relevance Heat
primary somatosensory cortex 30 90.40 High High
cerebral cortex 2 73.92 Quite High
imagery 29 73.28 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Somatosensory cortex 2 5.00 Very Low Very Low Very Low
long-term potentiation 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 12 99.46 Very High Very High Very High
Sprains And Strains 88 87.68 High High
Aging 1 45.44 Quite Low
Injury 3 5.00 Very Low Very Low Very Low
Brain Injury 3 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Nervous System Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The shapes of both V1 and the PMBSF are increased in rostral extent in ne-Emx2 mice, although the changes in PMBSF shape are also more complex.
Positive_regulation (increased) of V1
1) Confidence 0.27 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1578583 Disease Relevance 0.22 Pain Relevance 0.12
Transgenic ne-Emx2 mice showed a 52% increase in V1, a 25% decrease in PMBSF, and a 36% decrease in motor cortex.
Positive_regulation (increase) of V1 in cortex associated with targeted disruption
2) Confidence 0.27 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1578583 Disease Relevance 0.27 Pain Relevance 0.05
Binocular deprivation increases dendritic spine motility and turnover in mouse V1 in vivo [24],[25]; this provides an excellent model to correlate microglial behavior with the experience-dependent modification and elimination of synapses under non-pathological conditions.
Positive_regulation (increases) of V1 in synapses
3) Confidence 0.09 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2970556 Disease Relevance 0 Pain Relevance 0.06

General Comments

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