INT197446

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Context Info
Confidence 0.56
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 10
Total Number 10
Disease Relevance 3.78
Pain Relevance 2.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (Psmd1) cellular_component (Psmd1)
Anatomy Link Frequency
cleavage 1
taste bud 1
Psmd1 (Mus musculus)
Pain Link Frequency Relevance Heat
primary somatosensory cortex 127 100.00 Very High Very High Very High
Anterior cingulate cortex 134 99.80 Very High Very High Very High
Morphine 176 99.44 Very High Very High Very High
narcan 12 97.56 Very High Very High Very High
Nicotine 8 90.56 High High
Inflammation 65 89.68 High High
Dopamine 1 88.80 High High
Pain 29 88.00 High High
Enkephalin 66 85.72 High High
Multiple sclerosis 33 80.24 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 209 96.36 Very High Very High Very High
Dysgeusia 1 96.28 Very High Very High Very High
Nociception 60 92.44 High High
INFLAMMATION 65 89.68 High High
Multiple Sclerosis 71 89.32 High High
Infection 113 88.48 High High
Pain 23 88.00 High High
Sprains And Strains 146 84.68 Quite High
Demyelinating Disease 230 84.56 Quite High
Disease 41 83.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effect of morphine on simultaneously recorded responses in the S1 and ACC
Localization (responses) of S1 associated with primary somatosensory cortex, anterior cingulate cortex and morphine
1) Confidence 0.56 Published 2008 Journal Mol Pain Section Body Doc Link PMC2569012 Disease Relevance 0.43 Pain Relevance 1.28
The current source density (CSD) method can be used to accurately localize the synaptic action by input signals from the S1 and ACC.
Localization (localize) of S1 associated with primary somatosensory cortex and anterior cingulate cortex
2) Confidence 0.56 Published 2008 Journal Mol Pain Section Body Doc Link PMC2569012 Disease Relevance 0.35 Pain Relevance 0.95
Global differences: V1, S1, A1
Localization (differences) of S1 associated with primary somatosensory cortex
3) Confidence 0.50 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1578583 Disease Relevance 0.29 Pain Relevance 0.10
The A subunit S1, is subsequently released into the cytoplasm where it interferes with the inhibitory activity of Gi proteins unleashing intracellular signaling [12].
Localization (released) of S1
4) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012729 Disease Relevance 1.36 Pain Relevance 0.25
Taste buds were in the same locations in CV and foliate papillae (Figures S1 and S3), cellular appearances were similar, and mean taste bud area (WT: 1,336±41 mm2 vs. null: 1,342±46 mm2, p?
Localization (papillae) of S1 in taste bud
5) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939079 Disease Relevance 0.10 Pain Relevance 0
They also differ in their cleavage signal site whereby MHV-A59 S is cleaved posttranslationally into S1 and S2 subunits, but MHV-2 S protein is not cleaved and unable to cause fusion in vivo and in vitro.
Localization (cleaved) of S1 in cleavage
6) Confidence 0.24 Published 2010 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2905936 Disease Relevance 0.73 Pain Relevance 0.10
The combined set of 910 genes used for our analysis of SNP microarrays is available as a spreadsheet in supporting file S1.
Localization (supporting) of S1
7) Confidence 0.22 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2668711 Disease Relevance 0 Pain Relevance 0.09
Immunoprecipitation of podocin from the S1 and S2 fractions of the control glomeruli revealed that nephrin was more effectively coprecipitated from the S2 fraction as compared to the S1 fraction.
Localization (Immunoprecipitation) of S1
8) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2614475 Disease Relevance 0 Pain Relevance 0
The data were processed using WebArray [17], as described in Materials & Methods, and are presented in Table S1, and visualized by genome position in Figure 3.
Localization (presented) of S1
9) Confidence 0.06 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2698986 Disease Relevance 0.51 Pain Relevance 0
In Figure 3A the monomer release profile of wild-type GnRH (S12) and the short-acting analog S1, neither of which form fibrils after 30 d of incubation (Figures 1 and 2), are shown.
Localization (release) of S1
10) Confidence 0.04 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2225439 Disease Relevance 0 Pain Relevance 0.03

General Comments

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