INT197500

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Context Info
Confidence 0.32
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.51
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Egr3) intracellular (Egr3) DNA binding (Egr3)
Anatomy Link Frequency
nucleus 1
bowel 1
Egr3 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 2 95.44 Very High Very High Very High
Hippocampus 10 91.92 High High
Pyramidal cell 1 86.96 High High
medulla 1 85.44 High High
amygdala 2 82.80 Quite High
Inflammation 28 50.00 Quite Low
Pain 4 36.48 Quite Low
long-term potentiation 8 29.72 Quite Low
Inflammatory mediators 2 17.20 Low Low
substance P 22 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colorectal Cancer 62 97.12 Very High Very High Very High
Polyps 2 94.44 High High
Cancer 12 81.00 Quite High
Anxiety Disorder 38 52.16 Quite High
INFLAMMATION 33 50.00 Quite Low
Peripheral Neuropathy 3 45.60 Quite Low
Neuropathic Pain 2 40.64 Quite Low
Charcot Marie Tooth Disease 2 39.68 Quite Low
Disease 3 37.52 Quite Low
Death 7 37.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to Egr1 and Egr3, Egr2 protein has been detected in both the nucleus and cytoplasm of forebrain neurons (De et al., 2003; Mack et al., 1992).
Localization (detected) of Egr3 in nucleus
1) Confidence 0.32 Published 2007 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2525857 Disease Relevance 0 Pain Relevance 0.26
The order of predominance for the different TREs was: cRel, v-Myb, CRE-BP1/c-Jun, USF, AP-1_Q2, Pax-6, AP-1_C, NF-kappaB_Q6, Efr-1, Egr-3, and AREB6 (Figure 6 and Table 1 [additional file 1]).


Localization (was) of Egr-3
2) Confidence 0.22 Published 2007 Journal BMC Urol Section Body Doc Link PMC1888709 Disease Relevance 0 Pain Relevance 0
Whilst data saturation was reached, a convenience sample was used to recruit non-pilot GPs which may have been biased towards individuals holding positive attitudes regarding screening for bowel cancer.
Localization (biased) of pilot in bowel associated with colorectal cancer
3) Confidence 0.22 Published 2006 Journal BMC Fam Pract Section Body Doc Link PMC1584239 Disease Relevance 0.32 Pain Relevance 0
Pilot GPs anticipated patient queries from either patients requiring assistance with completing the test, or patients who were worried about the screening process or their results.
Localization (anticipated) of Pilot
4) Confidence 0.22 Published 2006 Journal BMC Fam Pract Section Body Doc Link PMC1584239 Disease Relevance 0.19 Pain Relevance 0

General Comments

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