INT197557

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Context Info
Confidence 0.44
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NFE2L2) plasma membrane (NFE2L2) nucleus (NFE2L2)
DNA binding (NFE2L2) cytoplasm (NFE2L2)
NFE2L2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 42.60 Quite Low
Glutamate 1 30.64 Quite Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 8 88.72 High High
Apoptosis 3 65.52 Quite High
Cancer 104 61.64 Quite High
Lung Cancer 54 60.08 Quite High
Adenocarcinoma 7 56.48 Quite High
INFLAMMATION 2 42.60 Quite Low
Disease 3 8.32 Low Low
Non-small-cell Lung Cancer 24 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 4 5.00 Very Low Very Low Very Low
Nicotine Addiction 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Kelch repeats of KEAP1 bind the Neh2 domain of NRF2, whereas the IVR and BTB domains are required for the redox-sensitive regulation of NRF2 through a series of reactive cysteines present throughout this region [22].
Positive_regulation (required) of Regulation (regulation) of NRF2
1) Confidence 0.44 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1584412 Disease Relevance 0.56 Pain Relevance 0

General Comments

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