INT197571

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Context Info
Confidence 0.48
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NFE2L2) plasma membrane (NFE2L2) nucleus (NFE2L2)
DNA binding (NFE2L2) cytoplasm (NFE2L2)
NFE2L2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 75.00 Quite High
Glutamate 1 63.04 Quite High
palliative 1 6.64 Low Low
Disease Link Frequency Relevance Heat
Apoptosis 3 97.92 Very High Very High Very High
Cancer 104 94.04 High High
Stress 8 92.20 High High
INFLAMMATION 2 75.00 Quite High
Non-small-cell Lung Cancer 24 21.04 Low Low
Lung Cancer 54 9.72 Low Low
Adenocarcinoma 7 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 4 5.00 Very Low Very Low Very Low
Nicotine Addiction 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Phosphorylation of NRF2 by protein kinase(s) associated with the MAPK/ERK signaling cascade increases stabilization of NRF2 and has been proposed as an important mechanism leading to increased expression of ARE-dependent genes [11].
Positive_regulation (increases) of Phosphorylation (Phosphorylation) of NRF2
1) Confidence 0.48 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1584412 Disease Relevance 0.44 Pain Relevance 0.07

General Comments

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